DL-Carnitine - ≥98% , CAS No.461-06-3

CAS: 461-06-3 Cat. No.: D413371 Formula: C₇H₁₅NO₃ Peso molecolare: 161.2

GRADE & PURITY ≥98%

Synonyms

(±)-Carnitin1-​Propanaminium,3-​carboxy-​2-​hydroxy-​N,​N,​N-​trimethyl-​,inner salt | Carnitina | Carnitine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Information

DL-Carnitine ((±)-Carnitin) is a racemic mixture of L-Carnitine and D-Carnitine that regulatesfatty acid transportin the mitochondrion. DL-carnitine is found to be ineffective or toxic, for example, to muscle cells and to the myocardium. DL-Carnitine causes symptoms of myasthenia and cardiac arrhythmias.

Specifications

Sinonimi

(±)-Carnitin1-​Propanaminium,3-​carboxy-​2-​hydroxy-​N,​N,​N-​trimethyl-​,inner salt | Carnitina | Carnitine

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

DL-Carnitine ((±)-Carnitin) is a racemic mixture of L-Carnitine and D-Carnitine that regulates fatty acid transport in the mitochondrion. DL-carnitine is found to be ineffective or toxic, for example, to muscle cells and to the myocardium. DL-Carnitine ca

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 504750375
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504750375
• Sorrisi canonici: C[N+](C)(C)CC(CC(=O)[O-])O
• IUPAC Name: 3-hydroxy-4-(trimethylazaniumyl)butanoate
• InChIKey: PHIQHXFUZVPYII-UHFFFAOYSA-N
• INCHI: 1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3
• Isomeri SMILES: C[N+](C)(C)CC(CC(=O)[O-])O
• CAS alternativo: 406-76-8
• Peso molecolare: 161.2
• Reaxy-Rn: 1866665
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1866665&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Classe Organonitrogen compounds
      • Subclass Quaternary ammonium salts

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Classe: Organonitrogen compounds
• Subclass: Quaternary ammonium salts
• Intermediate Tree Nodes: Not available
• Direct Parent: Carnitines
• Alternative Parents: Short-chain hydroxy acids and derivatives Beta hydroxy acids and derivatives Fatty acids and conjugates Tetraalkylammonium salts Secondary alcohols Carboxylic acid salts 1,2-aminoalcohols Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic zwitterions Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Carnitine - Beta-hydroxy acid - Short-chain hydroxy acid - Fatty acid - Hydroxy acid - Tetraalkylammonium salt - 1,2-aminoalcohol - Carboxylic acid salt - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxygen compound - Organooxygen compound - Organic zwitterion - Organic salt - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Amine - Alcohol - Aliphatic acyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as carnitines. These are organic compounds containing the quaternary ammonium compound carnitine.
• External Descriptors: a D,L-carnitine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

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SLC22A16 Tbio Solute carrier family 22 member 16 (4 Activities)

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Obiettivi associati (non umani)

Slc25a20 Carnitine/acylcarnitine translocase (26 Activities)

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Slc22a5 Solute carrier family 22 member 5 (44 Activities)

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Slc22a4 Solute carrier family 22 member 4 (11 Activities)

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Slc22a21 Solute carrier family 22 member 21 (8 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro DMSO: 32 mg/mL (198.51 mM); Water: 32 mg/mL (198.51 mM); Ethanol: Insoluble
• Peso molecolare: 161.200 g/mol
• XLogP3: -0.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 161.105 Da
• Monoisotopic Mass: 161.105 Da
• Topological Polar Surface Area: 60.400 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 134.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Riferimenti

1. Weili Li, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Shuhan Men, Ye Yuan, Yuying Fan.  (2022)  Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy.  Food & Function,  14  (2): (1024-1036).  [PMID:36562271] [10.1039/D2FO02026B]