DL-Serine hydroxamate - ≥97% , CAS No.55779-32-3

CAS: 55779-32-3 Cat. No.: D485325 Formula: C₃H₈N₂O₃ Peso molecolare: 120.11

GRADE & PURITY ≥97%

Synonyms

(+-)-serine hydroxamate | HY-131894 | DL-Serine hydroxamate | dl-serine hydroxa-mate | DTXSID301301599 | DL-Serine hydroxamate, seryl-tRNA synthetase inhibitor | Q27145350 | CHEBI:75494 | N-hydroxyserinamide | Propanamide, 2-amino-N,3-dihydroxy-, (A+/-)-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Description

Serine has been used as an inhibitor of seryl-tRNA synthetase. DL-Serine hydroxamate is used to induce metabolic synthesis of guanosine 3′-diphosphate 5′-diphosphate (ppGpp) inE. coliby amino acid starvation. It is also used to synchronize cell cycle inE. colicultures by inhibition of tRNA charging.

Specifications

Sinonimi

(+-)-serine hydroxamate | HY-131894 | DL-Serine hydroxamate | dl-serine hydroxa-mate | DTXSID301301599 | DL-Serine hydroxamate, seryl-tRNA synthetase inhibitor | Q27145350 | CHEBI:75494 | N-hydroxyserinamide | Propanamide, 2-amino-N,3-dihydroxy-, (A+/-)-

Specifiche e purezza

≥97%

Meccanismi biochimici e fisiologici

Serine is involved in the one-carbon unit metabolism. It is associated with the biosynthesis of cysteine, ceramide, phosphatidylserine, purine and pyrimidine. In bacteria, it participates in tryptophan synthesis. Gluconeogenesis, one of the important bioc

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

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Purezza

≥97%

Nomi e identificatori

Pubchem Sid

528764155

Sorrisi canonici

C(C(C(=O)NO)N)O

IUPAC Name

2-amino-N,3-dihydroxypropanamide

InChIKey

LELJBJGDDGUFRP-UHFFFAOYSA-N

INCHI

1S/C3H8N2O3/c4-2(1-6)3(7)5-8/h2,6,8H,1,4H2,(H,5,7)

Isomeri SMILES

C(C(C(=O)NO)N)O

Peso molecolare

120.11

Reaxy-Rn

2429002

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2429002&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Classe Organooxygen compounds
      • Subclass Alcohols and polyols

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Classe: Organooxygen compounds
• Subclass: Alcohols and polyols
• Intermediate Tree Nodes: Not available
• Direct Parent: Primary alcohols
• Alternative Parents: Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary alcohol - Organonitrogen compound - Primary aliphatic amine - Amine - Aliphatic acyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as primary alcohols. These are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
• External Descriptors: hydroxamic acid - serine derivative

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Meccanismi d'azione

Proprietà chimiche e fisiche

• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable
• Peso molecolare: 120.110 g/mol
• XLogP3: -2.500
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 120.053 Da
• Monoisotopic Mass: 120.053 Da
• Topological Polar Surface Area: 95.600 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 84.600
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1