DOTAP methylsulfate - Moligand™, 10 mM in DMSO , CAS No.144189-73-1

CAS: 144189-73-1 Cat. No.: D1500872 Molecular Weight: 774.19

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

DOTAP Transfection Reagent is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC.COS(=O)(=O)[O-]
• WGK Germany: 3
• Molecular Weight: 774.19
• Reaxy-Rn: 34197390
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34197390&ln=

Chemical and Physical Properties

• Boil Point(°C): 100 °C
• Melt Point(°C): -5 °C

References

1. Binke Wang, Xinyu Qi, Ruping Yang, Xu Xu, Shiyao Li, Chunli Zhang, Haitao Yu.  (2025)  Cubosome-based co-delivery of doxorubicin and polydatin for targeted cancer therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.168855]

2. Yandong Xie, Xueying Lu, Zhen Wang, Mingxi Liu, Liang Liu, Ran Wang, Kun Yang, Hong Xiao, Jianyong Li, Xianglong Tang, Hongyi Liu.  (2022)  A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma.  Biomaterials Science,  10  (23): (6791-6803).  [PMID:36314541] [10.1039/D2BM01145J]