DPA-714 - 10mM in DMSO , CAS No.958233-07-3

CAS: 958233-07-3 Cat. No.: D656048 Formula: C₂₂H₂₇FN₄O₂ Peso molecolare: 398.47 PubChem CID: 24895172

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

DPA-714 is a high affinity translocator protein (TSPO) ligand ( K i =7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18F DPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model

In Vivo

[18F]DPA-714 binding significantly increases in vivo as a result of AD‐like pathology and age in APP swe ×PS1 Δe9 mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Ki: 7 nM (TSPO)

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

DPA-714 is a high affinity translocator protein (TSPO) ligand ( K i =7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18F DPA-714 successfully eval

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

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Nomi e identificatori

Isomeri SMILES

CCN(CC)C(=O)CC1=C2N=C(C=C(N2N=C1C3=CC=C(C=C3)OCCF)C)C

CAS alternativo

958233-07-3

PubChem CID

24895172

Termini MeSH

DPA 714;DPA-714;DPA714;N,N-diethyl-2-(2-(4-(2-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidin-3-yl)acetamide

Peso molecolare

398.47