(±)-Dropropizine - ≥97% , CAS No.17692-31-8

CAS: 17692-31-8 Cat. No.: D118870 Formula: C₁₃H₂₀N₂O₂ Peso molecolare: 236.31 Numero EC: 241-683-7

GRADE & PURITY ≥97%

Synonyms

HMS1921B07 | NSC-757820 | Prestwick1_000245 | Dropropizinum [INN-Latin] | NCGC00018230-05 | rac Dropropizine | 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol | 3-(4-phenylpiperazinyl)propane-1,2-diol | DROPROPIZINE [MI] | BSPBio_000030 | Tox21_110842_1 | Dopr

Storage

Room temperature

Shipped In

Normale

Specifications

Sinonimi

HMS1921B07 | NSC-757820 | Prestwick1_000245 | Dropropizinum [INN-Latin] | NCGC00018230-05 | rac Dropropizine | 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol | 3-(4-phenylpiperazinyl)propane-1,2-diol | DROPROPIZINE [MI] | BSPBio_000030 | Tox21_110842_1 | Dopr

Specifiche e purezza

≥97%

Meccanismi biochimici e fisiologici

Agente antitosse non oppioide. Racemato di levodropropizina ed enantiomero. Mostra effetti depressivi e antitussivi sul SNC in vivo. Attivo per via orale.

Condizioni di conservazione di stoccaggio

Room temperature

Spedito in

Normale

Nota

Per quanto possibile, si consiglia di preparare e utilizzare le soluzioni lo stesso giorno. Tuttavia, se è necessario preparare in anticipo le soluzioni di riserva, si consiglia di conservarle in aliquote in fiale ben chiuse a -20°C. In genere, queste possono essere utilizzate per un mese. In genere, queste soluzioni sono utilizzabili fino a un mese. Prima dell'uso e dell'apertura della fiala, si consiglia di lasciare che il prodotto si equilibri a temperatura ambiente per almeno 1 ora. Avete bisogno di ulteriori consigli su solubilità, uso e manipolazione? Per ulteriori informazioni, visitare la pagina delle domande frequenti (FAQ).

Purezza

≥97%

Nomi e identificatori

• Pubchem Sid: 508815919
• Sorrisi canonici: C1CN(CCN1CC(CO)O)C2=CC=CC=C2
• IUPAC Name: 3-(4-phenylpiperazin-1-yl)propane-1,2-diol
• InChIKey: PTVWPYVOOKLBCG-UHFFFAOYSA-N
• INCHI: 1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2
• Isomeri SMILES: C1CN(CCN1CC(CO)O)C2=CC=CC=C2
• WGK Germania: 3
• Peso molecolare: 236.31
• Reaxy-Rn: 615737
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=615737&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Diazinanes
      • Subclass Piperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylpiperazines
• Alternative Parents: N-arylpiperazines Dialkylarylamines Aniline and substituted anilines N-alkylpiperazines 1,3-aminoalcohols Trialkylamines Secondary alcohols 1,2-diols 1,2-aminoalcohols Azacyclic compounds Primary alcohols Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Phenylpiperazine - N-arylpiperazine - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - N-alkylpiperazine - Benzenoid - Monocyclic benzene moiety - 1,3-aminoalcohol - 1,2-diol - Tertiary aliphatic amine - Tertiary amine - 1,2-aminoalcohol - Secondary alcohol - Azacycle - Organopnictogen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Primary alcohol - Amine - Alcohol - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

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GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)

Discover Target: GLS

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Obiettivi associati (non umani)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

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Plasmodium falciparum (966862 Activities)

Explore this target

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Cavia porcellus (23802 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 236.310 g/mol
• XLogP3: 0.600
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 236.152 Da
• Monoisotopic Mass: 236.152 Da
• Topological Polar Surface Area: 46.900 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 211.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Riferimenti

1. Zhenhe Chen, Jianling Sun, Yong He, Tingting Zhang, Run Hao, Aijun Shi, Eduardo Enciso.  (2018)  Enhanced fluorescence detection of enrofloxacin with curved-surface responsive inverse opal polymers and molecular imprinting.  Analytical Methods,  11  (8): (1043-1052).  [PMID:] [10.1039/C8AY02329H]