10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC 50 of 0.28 μM for USP8
In Vitro
DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC 50 of 0.28 μM, and has no effect on USP7, with an IC 50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC 50 values of 0.5-1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 0.28 μM (USP8)
Specifications
Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC 50 of 0.28 μM for USP8.
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
INHIBITOR
Nomi e identificatori
Peso molecolare
275.26
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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