10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application
In Vitro
DVD-445 (Compound 7) shows a cytotoxic effect in SH-SY5Y, U87, HaCaT cell lines and PBMCs with IC 50 s of 10.99 μM, 9.70 μM, 8.30 μM, 55.71 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 0.60 μM (rat TrxR1)
Specifications
Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application.
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Nomi e identificatori
Peso molecolare
458.50
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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