Dyrk1A-IN-5 - ≥98% , CAS No.1685235-41-9

CAS: 1685235-41-9 Cat. No.: D648978 Formula: C16H9IN2O2 Peso molecolare: 388.16
Disponibile su ordine
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Germania (EU)
USA*
Price
Qty
5mg
D648978-5mg
Su ordinazione · 8–12 settimane
556,13€
10mg
D648978-10mg
Su ordinazione · 8–12 settimane
885,87€
25mg
D648978-25mg
Su ordinazione · 8–12 settimane
1.823,03€
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC 50 of 6 nM. Dyrk1A-IN-5 dose-dependently reduces the phosphorylation of Thr434 in SF3B1, with an IC 50 of 0.5 μM. Dyrk1A-IN-5 inhibits phosphorylation of tau at Thr212, with an IC 50 of 2.1 μM. Dyrk1A-IN-5 can be used for Down syndrome research

Form:Solid

IC50& Target:DYRK1A 6 nM (IC 50 ) DYRK1B 600 nM (IC 50 ) DYRK2 >10000 nM (IC 50 )

Specifications

Specifiche e purezza
≥98%
Meccanismi biochimici e fisiologici
Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC 50 of 6 nM. Dyrk1A-IN-5 dose-dependently reduces the phosphorylation of Thr434 in SF3B1, with an IC 50 of 0.5 μM. Dyrk1A-IN-5 inhibits phosphorylation of tau at Thr212, with
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
INHIBITOR
Purezza
≥98%
Nomi e identificatori
Peso molecolare 388.16

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

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