(-)-Eburnamonina - Moligand™, ≥99% , Allosteric modulator of M 1 receptor;Allosteric modulator of M 2 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 4 receptor, CAS No.4880-88-0, Allosteric modulator of M 1 receptor;Allosteric modulator of M 2 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 4 receptor

Name: (-)-Eburnamonina - Moligand™, ≥99% , Allosteric modulator of M 1 receptor;Allosteric modulator of M 2 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 4 receptor, CAS No.4880-88-0, Allosteric modulator of M 1 receptor;Allosteric modulator of M 2 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 4 receptor
SKU: E348350
Availability: InStock

CAS: 4880-88-0 Cat. No.: E348350 Formula: C₁₉H₂₂N₂O Peso molecolare: 294.39 Beilstein Registry Number: 4706903 Numero EC: 225-490-5

COA

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(-)-Eburnamonina - Moligand™, ≥99% CAS No(4880-88-0) by Aladdin Scientific

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Disponibile su ordine

GRADE & PURITY Moligand™ ? ≥99%

Synonyms

HY-B1180 | NCIStruc2_000870 | 2-((6-(Benzylamino)-9-methyl-9H-purin-2-yl)amino)ethanol | 2-Methyldiphenhydramine | C09149 | Eburnamin-14(15H)-one, (3-alpha,16-alpha)- | (-)-Vincamone | GTPL345 | IDI1_000411 | CH-846 | DB13793 | HMS2096J16 | AC-26459 | BS-

Storage

Conservare a -20°C

Shipped In

Cassetta del ghiaccio + cuscini per il ghiaccio

Panoramica Specifications Proprietà del prodotto Nomi e identificatori Documentazione Advanced Data Taxonomic Classification Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Calcolatori di soluzioni Recensioni Domande frequenti

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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Conservare a -20°C Ships Cassetta del ghiaccio + cuscini per il ghiaccio Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

la (-)-Eburnamonina è un vasodilatatore che agisce anche come stimolante metabolico cerebrale. Il composto è in grado di proteggere il cervello dei topi esposti all'intossicazione da cianuro di potassio. Gli studi dimostrano che la (-)-Eburnamonina aumenta l'affinità dell'acetilcolina sui recettori M2 e M4, così come aumenta l'affinità del carbacholo, del betanecolo, del furmetide, del metilfurmetide, del pentiltio-TZTP, della pilocarpina, dell'oxotremorina e dell'oxotremorina-M sui recettori M2. Le ricerche dimostrano anche che la (-)-Eburnamonina ha effetti anti-ipossici.

Specifications

Sinonimi

Specifiche e purezza

Moligand™, ≥99%

Condizioni di conservazione di stoccaggio

Conservare a -20°C

Spedito in

Cassetta del ghiaccio + cuscini per il ghiaccio

Grado

Moligand™

Tipo di azione

ALLOSTERIC MODULATOR

Meccanismo d'azione

Allosteric modulator of M 1 receptor;Allosteric modulator of M 2 receptor;Allosteric modulator of M 3 receptor;Allosteric modulator of M 4 receptor

Purezza

≥99%

Proprietà del prodotto

pKa

pKa: 8.13

Nomi e identificatori

Pubchem Sid

504754610

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504754610

Sorrisi canonici

CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2

IUPAC Name

(15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one

InChIKey

WYJAPUKIYAZSEM-MOPGFXCFSA-N

INCHI

1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1

Isomeri SMILES

CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2

WGK Germania

RTECS

YY8575570

Peso molecolare

294.39

Beilstein

4706903

Reaxy-Rn

759171

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=759171&ln=

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Alkaloids and derivatives
  - Classe Eburnan-type alkaloids

Kingdom	Organic compounds
Superclass	Alkaloids and derivatives
Classe	Eburnan-type alkaloids
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Eburnan-type alkaloids
Alternative Parents	Indolonaphthyridine alkaloids Beta carbolines 3-alkylindoles Naphthyridines Aralkylamines Piperidines Benzenoids Pyrroles Heteroaromatic compounds Trialkylamines Lactams Azacyclic compounds Organic oxides Organooxygen compounds Organopnictogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Eburna alkaloid - Indolo[3,2-1de][1,5]naphthyridine - Beta-carboline - Pyridoindole - Diazanaphthalene - Naphthyridine - 3-alkylindole - Indole - Indole or derivatives - Aralkylamine - Piperidine - Benzenoid - Heteroaromatic compound - Pyrrole - Tertiary amine - Lactam - Tertiary aliphatic amine - Azacycle - Organoheterocyclic compound - Amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
Descrizione	This compound belongs to the class of organic compounds known as eburnan-type alkaloids. These are alkaloids with a structure based on the eburnan skeleton, that arises from rearrangement of the aspidospermidine ring system, involving migration of C-21 from C-7 to C-2, fission of the 2,16-bond, and attachment of C-16 to N-1.
External Descriptors	Indole alkaloids
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Struttura 3D

Obiettivi associati (umani)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 (1 Activities)

Discover Target: CHRM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 (1 Activities)

Discover Target: CHRM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM2 Tclin Muscarinic acetylcholine receptor M2 (1 Activities)

Discover Target: CHRM2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (1 Activities)

Discover Target: CHRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Data	Oggetto
K2209561	Certificate of Analysis	Jul 19, 2022	E348350
K2209562	Certificate of Analysis	Jul 19, 2022	E348350
K2209570	Certificate of Analysis	Jul 19, 2022	E348350

Solubilità	Soluble in chloroform.
Indice di rifrazione	n20D1.72 (Predicted)
Rotazione specifica [α]	α20/D -94.5°±2°, c = 1 in chloroform
Punto di ebollizione (°C)	441.88° C at 760 mmHg (Predicted)
Punto di fusione (°C)	174-176°C
Peso molecolare	294.400 g/mol
XLogP3	3.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	294.173 Da
Monoisotopic Mass	294.173 Da
Topological Polar Surface Area	25.200 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	492.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Storage & shipping

Quality documents

Literature proof

Panoramica

Specifications

Documentazione

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

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