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Emprumapimod hydrochloride , CAS No.E658976
AVAILABLE TO ORDER
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Emprumapimod (PF-07265803) hydrochloride is an orally active and selective inhibitor of p38α MAPK . Emprumapimod hydrochloride can be used for the research of dilated cardiomyopathy and acute inflammatory pain.
Appearance:Solid
IC50& Target:p38α
In Vitro:Emprumapimod hydrochloride (ARRY-797) inhibits LPS-induced IL-6 production in RPMI-8226 cell with an IC 50 value of 100 pM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo:Emprumapimod hydrochloride (ARRY-797) (30mg/kg; p.o.) inhibits the expression of IL-6 (91%) and TNF-α (95%) in SCID-beige mice, inhibits the phosphorylation of p38 in RPMI-8226 xenografts, inhibits the growth of RPMI-8226 tumour (72%) in multiple myeloma
Biological Activity:Emprumapimod (PF-07265803) hydrochloride is an orally active and selective inhibitor of p38α MAPK . Emprumapimod hydrochloride can be used for the research of dilated cardiomyopathy and acute inflammatory pain .
Specifications
Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
| Molecular Weight | 509.98 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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