Epetraborole hydrochloride - 10mM in DMSO , CAS No.1234563-16-6

CAS: 1234563-16-6 Cat. No.: E655874 Formula: C₁₁H₁₇BClNO₄ Peso molecolare: 273.52 Numero EC: 689-184-7

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research

In Vitro

Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: Anaerobes isolates Concentration: 0-32 μg/mL Incubation Time: Result: Showed MIC 50 /MIC 90 for all anaerobes isolates tested of 2 and 4 μg/mL, respectively.

IC50& Target:IC 50 : 0.31 μM (LeuRS)

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research

Condizioni di conservazione di stoccaggio

Desiccated,Store at -80°C

Spedito in

Dry ice packs + Cold packs

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Tipo di azione

INHIBITOR

Nomi e identificatori

Isomeri SMILES

B1(C2=C(C=CC=C2OCCCO)[C@H](O1)CN)O.Cl

CAS alternativo

1234563-16-6;1093643-37-8

Peso molecolare

273.52