Epiandrosterone - 10mM in DMSO , CAS No.481-29-8

CAS: 481-29-8 Cat. No.: E407759 Formula: C₁₉H₃₀O₂ Peso molecolare: 290.4 Numero EC: 207-563-3

QUALITÀ & PUREZZA 10mM in DMSO

Synonyms

3β-androsterone, EpiA | 3β-Hydroxy-5α-androstane-17-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Epiandrosterone Epiandrosterone (3β-androsterone, EpiA) is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA.
In vitro

Epiandrosterone is a natural metabolite of dehydroepiandrosterone (DHEA) via the 5α-reductaseenzyme. Epiandrosterone is formed in peripheral tissues, from which it is released into the circulation and is ultimately excreted in the urine. Epiandrosterone is only a weak androgen, but it is widely recognized to inhibit the pentosephosphate pathway (PPP) and to decrease intracellular NADPH levels. Epiandrosterone attenuates NO-evoked relaxation of pulmonary artery , although it inhibits angiotensin II- and hypoxia-induced vasoconstriction in isolated lungs and relaxes isolated pulmonary arteries pre-constricted with KCl.

In vivo

Cell Data

cell lines：MES-SA, MDA-MB-468, MCF-7, HCT116, HT29, U87MG, PC-3 and DU145 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifiche

Sinonimi

3β-androsterone, EpiA | 3β-Hydroxy-5α-androstane-17-one

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Epiandrosterone (3β-androsterone, EpiA) is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

AGONIST

Nomi e identificatori

Isomeri SMILES

C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O

Peso molecolare

290.4

Reaxy-Rn

2055720

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2055720&ln=