Esomeprazole sodium - 10mM in DMSO , Potassium-transporting ATPase inhibitor, CAS No.161796-78-7, Potassium-transporting ATPase inhibitor

CAS: 161796-78-7 Cat. No.: E408295 Molecular Weight: 367.41 EC Number: 620-470-6

GRADE & PURITY 10mM in DMSO

Synonyms

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Esomeprazole sodium Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3, 5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

Potassium-transporting ATPase inhibitor

Names and Identifiers

• Isomeric SMILES: CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C([N-]2)C=C(C=C3)OC.[Na+]
• Molecular Weight: 367.41
• Reaxy-Rn: 11512125
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11512125&ln=

Chemical and Physical Properties

• Boil Point(°C): 600°C
• Melt Point(°C): 229 °C

References

1. Xiao-yu Xu, Zhe-yan Zhang, Xiao-dan Zhang, Jian-chao Luo, Yun-shan Zhong, Le-hao Jin, Da-peng Dai, Jian-chang Qian.  (2024)  Critical considerations for co-administering rivaroxaban and vonoprazan: Unveiling potential pharmacokinetic interactions.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:39643151] [10.1016/j.cbi.2024.111342]