Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

3-Mercaptopropionic acid, 3-MPA

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Sandra Forbes

 

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Using 3-mercaptopropionic acid as a reducing agent and a catalytic amount of either NBS or I2 in acetonitrile at ambient temperature, various alkyl and aryl sulfoxides have been successfully deoxygenated. Notably, under these reaction conditions, acid-sensitive substrates, such as acetals, remained undisturbed.
B. Karimi, D. Zareyee, 
Synthesis, 2003, 1875-1877.

DOI: 10.1055/s-2003-40981

 

 

Quoted from: https://www.organic-chemistry.org/chemicals/reductions/3-mercaptopropionic-acid.shtm

 

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Aladdin Scientific. "3-Mercaptopropionic acid, 3-MPA" Aladdin Knowledge Base, updated 9 nov 2026. https://www.aladdinsci.com/eu_it/faqs/3-mercaptopropionic-acid-3-mpa-en.html
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