Topic

Cross-coupling

Browse protocols, FAQs, guidelines, and technical articles tagged “Cross-coupling”, newest first. For research use only.

96 resources · protocols, FAQs, guidelines & articles
Article

Phosphine Ligand Selection Guide: How to Simultaneously Lower the Ar–Cl Activation Barrier, Improve Catalyst Longevity, and Stabilize the Impurity Profile in Pd-Catalyzed Cross-Coupling (Tables 1–4 Included)

In cross-coupling (especially Pd-catalyzed C–N/C–C bond formation), researchers often set multiple goals at once: more challenging substrates (Ar–Cl/heteroaryl chlorides), less metal (low Pd loading), larger scale (scale-up), and tighter control of outcomes (stable impurity profile and ...

Updated ·26 min read
Article

Photoredox Iridium Catalyst for Single Electron Transfer (SET) Cross-Coupling

C(sp2)- and C(sp)-hybridized coupling reactions are established catalytic approaches. However, multi-step C(sp3)- and C(sp2)-coupling reactions of boronic acids and related derivatives are still limited by ineffective two-electron transmetalation reactions. These conventional protocols exhibit ...

Updated ·2 min read

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