≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Fasnall Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity.
Targets
FASN
| Canonical Smiles | CC1=C(SC2=NC=NC(=C12)NC3CCN(C3)CC4=CC=CC=C4)C |
|---|---|
| IUPAC Name | N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine |
| InChIKey | VSXRMURGJRAOCU-UHFFFAOYSA-N |
| INCHI | 1S/C19H22N4S/c1-13-14(2)24-19-17(13)18(20-12-21-19)22-16-8-9-23(11-16)10-15-6-4-3-5-7-15/h3-7,12,16H,8-11H2,1-2H3,(H,20,21,22) |
| Isomeric SMILES | CC1=C(SC2=NC=NC(=C12)NC3CCN(C3)CC4=CC=CC=C4)C |
| Molecular Weight | 338.47 |
| Reaxy-Rn | 31884835 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31884835&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Thienopyrimidines |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Thienopyrimidines |
| Alternative Parents | Phenylmethylamines Benzylamines Secondary alkylarylamines Aralkylamines Aminopyrimidines and derivatives N-alkylpyrrolidines Imidolactams Thiophenes Heteroaromatic compounds Trialkylamines Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Thienopyrimidine - Phenylmethylamine - Benzylamine - Aralkylamine - Secondary aliphatic/aromatic amine - Aminopyrimidine - Imidolactam - Benzenoid - N-alkylpyrrolidine - Pyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Thiophene - Pyrrolidine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Secondary amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as thienopyrimidines. These are heterocyclic compounds containing a thiophene ring fused to a pyrimidine ring. Thiophene is 5-membered ring consisting of four carbon atoms and one sulfur atom. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2402623 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402624 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402625 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402628 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402629 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402630 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402631 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402632 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402633 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402634 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| B2402635 | Certificate of Analysis | Dec 28, 2023 | F413416 |
| Solubility | Solubility (25°C) In vitro Ethanol: 25 mg/mL (73.86 mM); DMSO: 13 mg/mL (38.4 mM); Water: Insoluble; |
|---|---|
| Molecular Weight | 338.500 g/mol |
| XLogP3 | 4.400 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 338.157 Da |
| Monoisotopic Mass | 338.157 Da |
| Topological Polar Surface Area | 69.300 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 414.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Chen Zixiang, Niu Kaifeng, Li Mengge, Deng Yuchun, Zhang Ji, Wei Di, Wang Jiaqi, Zhao Yongliang. (2025) GCLC desuccinylation regulated by oxidative stress protects human cancer cells from ferroptosis. CELL DEATH AND DIFFERENTIATION, [PMID:40188196] [10.1038/s41418-025-01505-8] |
