FH1 (BRD-K4477) - ≥98% , CAS No.2719-05-3

CAS: 2719-05-3 Cat. No.: F413757 Formula: C₁₇H₁₈N₂O₂ Peso molecolare: 282.34 Numero EC: 665-398-6

GRADE & PURITY ≥98%

Synonyms

N,N'-AcetylMDA | AC-33028 | N,N'-Diacetyl-4,4'-diaminodiphenylmethane | Paroil chlorez | Acetamide,N'-(methylenedi-4,1-phenylene)bis- | N,N'-(Methylenedi-4,1-phenylene)bis- acetamide | N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide | AM85691 | AKOS00281

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Information

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

In vitro

FH1(BRD-K4477) enhances hepatocyte functions, and promotes the maturation of well-differentiated cultures of iHeps, which potentially alleviates a major obstacle to the use of iPS cells as a renewable source of functional human hepatocytes.

Specifications

Sinonimi

N,N'-AcetylMDA | AC-33028 | N,N'-Diacetyl-4,4'-diaminodiphenylmethane | Paroil chlorez | Acetamide,N'-(methylenedi-4,1-phenylene)bis- | N,N'-(Methylenedi-4,1-phenylene)bis- acetamide | N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide | AM85691 | AKOS00281

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

504756248

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504756248

Sorrisi canonici

CC(=O)NC1=CC=C(C=C1)CC2=CC=C(C=C2)NC(=O)C

IUPAC Name

N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide

InChIKey

OEXMNSOPAKOPEF-UHFFFAOYSA-N

INCHI

1S/C17H18N2O2/c1-12(20)18-16-7-3-14(4-8-16)11-15-5-9-17(10-6-15)19-13(2)21/h3-10H,11H2,1-2H3,(H,18,20)(H,19,21)

Isomeri SMILES

CC(=O)NC1=CC=C(C=C1)CC2=CC=C(C=C2)NC(=O)C

Peso molecolare

282.34

Reaxy-Rn

2815695

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2815695&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Acetanilides N-acetylarylamines Acetamides Secondary carboxylic acid amides Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Diphenylmethane - Acetanilide - N-acetylarylamine - Anilide - N-arylamide - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (non umani)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: DMSO: 52 mg/mL (184.2 mM) Ethanol: <1 mg/mL
• Peso molecolare: 282.340 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 282.137 Da
• Monoisotopic Mass: 282.137 Da
• Topological Polar Surface Area: 58.200 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 320.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2719-05-3, the molecular formula is C17H18N2O2, and the molecular weight is 282.34 g/mol. InChIKey OEXMNSOPAKOPEF-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.