Filipin complex - 10mM in DMSO , CAS No.11078-21-0

CAS: 11078-21-0 Cat. No.: F656403 Formula: C₃₅H₅₈O₁₁ (for Filipin III) Peso molecolare: 654.80 Numero EC: 631-260-9

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Filipin complex is a potent polyene macrolide antifungal antibiotic . Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. Filipin complex compriss 70% filipin III and 5% other filipin homologues

In Vitro

Filipin complex (2 μg/ml; 1+48 h) inhibits PRRSV entry with respiratory syndrome virus (PRRSV) genome copies in infected cells reduced by 61% in MARC-145 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Macrolide

Specifications

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Filipin complex is a potent polyene macrolide antifungal antibiotic . Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of 70% filipin III and 5% of other filipin homolog

Condizioni di conservazione di stoccaggio

Protected from light,Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

• Isomeri SMILES: CCCCC[C@H]([C@@H]1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@@H](/C(=C/C=C/C=C/C=C/C=C/[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O)O
• CAS alternativo: 11078-21-0,480-49-9
• Termini MeSH: Desoxylagosin;Filimarisin;Filipin;Filipin I;Filipin II;Filipin III;Filipin IV;NSC 3364;NSC-3364;NSC3364;U 5956;U-5956;U5956
• Peso molecolare: 654.80
• Reaxy-Rn: 1339814
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1339814&ln=

Proprietà chimiche e fisiche

• Sensibilità: light sensitive

Riferimenti

1. Jianbo Li, Yaru Xu, Jieke Zhang, Qinglian Li, Chenxu Wang, Zhe Wu, Weijing Yang, Meng Xu, Zhenzhong Zhang, Lei Wang, Jinjie Zhang.  (2023)  Bioinspired fine-tuning of the mechanical rigidity of SNEDDS for the efficient crossing of multiple gastrointestinal barriers.  JOURNAL OF CONTROLLED RELEASE,      [PMID:37625600] [10.1016/j.jconrel.2023.08.044]

2. Peifu Xiao, Xiaoguang Tao, Hanxun Wang, Hongbing Liu, Yupeng Feng, Yueqi Zhu, Zhengzhen Jiang, Tian Yin, Yu Zhang, Haibing He, Jingxin Gou, Xing Tang.  (2023)  Enzyme/pH dual stimuli-responsive nanoplatform co-deliver disulfiram and doxorubicin for effective treatment of breast cancer lung metastasis.  Expert Opinion on Drug Delivery,      [PMID:37452715] [10.1080/17425247.2023.2237888]

3. Dan Li, Gaoyang Yi, Guifang Cao, Adam C. Midgley, Yongli Yang, Dan Yang, Wenguang Liu, Yujuan He, Xiaolin Yao, Guoliang Li.  (2025)  Dual-Carriers of Tartary Buckwheat-Derived Exosome-Like Nanovesicles Synergistically Regulate Glucose Metabolism in the Intestine-Liver Axis.  Small,      [PMID:40079102] [10.1002/smll.202410124]

Domande frequenti

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 11078-21-0, the molecular formula is C35H58O11 (for Filipin III), and the molecular weight is 654.80 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.