FITC-CM-Dextran

Cat. No.: F491452

Synonyms

FITC-carboxymethyl-dextran;Fluorescein isothiocyanate–Carboxymethyl–Dextran;

Storage

Protected from light,Room temperature,Argon charged

Shipped In

Normal

Panoramica

Product Describtion：

FITC-CM-dextrans are standard FITC-dextran carrying carboxymethyl-substituents. FITC-CM-dextrans have been developed for special studies on membranes and cells. The CM (carboxymethyl) group gives the product anionic (negative) charge. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-CM-dextrans from 4 kDa to 150 kDa. FITC-CM-dextran is supplied as a yellow powder.FITC-CM-dextrans are manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali whereby O-carboxymethyl groups are introduced along the dextran chain. The carboxyl content is approximately 5% which is equivalent to about one CM group for every five glucose units. Thereafter, fluorescein (FITC) groups are introduced by reaction with fluorescein isothiocyanate. The degree of substitution of FITC lies between 0.003 – 0.008.ApplicationFITC-CM-dextran are mostly used for studies of permeability and microcirculation. The carboxyl groups will impart an overall negative charge to the molecule, which may be valuable in gaining information on the permeability characteristics of cell membranes and tissues. The free carboxyl group is also useful for coupling other substances to the dextran chain.FITC-CM-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.fluorescent derivative of a carboxymethyl-dextran fraction produced from a dextran fraction with an average molecular weight of approx. 4000. It is supplied as a yellow powder which is readily soluble in water.

Product specifications and parameters:

SKU	NAME	Molecular Weight
F491452-4 kDa	FITC-CM-Dextran	4 kDa
F491452-20 kDa	FITC-CM-Dextran	20 kDa
F491452-40 kDa	FITC-CM-Dextran	40 kDa
F491452-70 kDa	FITC-CM-Dextran	70 kDa
F491452-150 kDa	FITC-CM-Dextran	150 kDa

Specifications

Sinonimi

FITC-carboxymethyl-dextran;Fluorescein isothiocyanate–Carboxymethyl–Dextran;

Condizioni di conservazione di stoccaggio

Protected from light,Room temperature,Argon charged

Spedito in

Normal

Proprietà chimiche e fisiche

• Solubilità: souble in water
• Sensibilità: light & air& moisture sensitive