fosmidomycin - Moligand™ , 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic inhibitor, CAS No.66508-53-0, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic inhibitor

CAS: 66508-53-0 Cat. No.: F610386 Formula: C₄H₁₀NO₅P Peso molecolare: 183.1 PubChem CID: 572

GRADE & PURITY Moligand™

Synonyms

CHEBI:443725 | GTPL9739 | 3-(N-hydroxyformamido)propylphosphonic acid | Fosmidomycine [INN-French] | Fosmidomycinum | GJXWDTUCERCKIX-UHFFFAOYSA-N | [3-(N-hydroxyformamido)propyl]phosphonic acid | 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | FR-31564 |

Storage

Room temperature

Specifications

Sinonimi

CHEBI:443725 | GTPL9739 | 3-(N-hydroxyformamido)propylphosphonic acid | Fosmidomycine [INN-French] | Fosmidomycinum | GJXWDTUCERCKIX-UHFFFAOYSA-N | [3-(N-hydroxyformamido)propyl]phosphonic acid | 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | FR-31564 |

Specifiche e purezza

Moligand™

Condizioni di conservazione di stoccaggio

Room temperature

Grado

Moligand™

Tipo di azione

INHIBITOR

Meccanismo d'azione

1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic inhibitor

Proprietà del prodotto

• ALogP: -2.2

Nomi e identificatori

• Sorrisi canonici: C(CN(C=O)O)CP(=O)(O)O
• IUPAC Name: 3-[formyl(hydroxy)amino]propylphosphonic acid
• InChIKey: GJXWDTUCERCKIX-UHFFFAOYSA-N
• INCHI: 1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10)
• Isomeri SMILES: C(CN(C=O)O)CP(=O)(O)O
• CAS alternativo: 66508-53-0,66508-37-0 (mono-hydrochloride salt)
• PubChem CID: 572
• Termini MeSH: 3-(N-formyl-N-hydroxy)aminopropylphosphonic acid;fosfidomycin;fosmidomycin;fosmidomycin monoammonium salt;fosmidomycin monopotassium salt;fosmidomycin monosodium salt;fosmidomycin sodium;fosmidomycin sodium salt;FR-31564;phosphonic acid, (3-(formylhydroxy
• Peso molecolare: 183.1

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Organic phosphonic acids and derivatives
      • Subclass Organic phosphonic acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Organic phosphonic acids and derivatives
• Subclass: Organic phosphonic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic phosphonic acids
• Alternative Parents: Hydroxamic acids Organopnictogen compounds Organophosphorus compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organophosphonic acid - Hydroxamic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organophosphorus compound - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as organic phosphonic acids. These are organic compounds containing phosphonic acid.
• External Descriptors: phosphonic acids - hydroxamic acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

Homo sapiens (32628 Activities)

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MRC5 (9203 Activities)

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Obiettivi associati (non umani)

ddlB D-alanylalanine synthetase (66 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase (389 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

tmk Thymidylate kinase (360 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dxr 1-deoxyxylulose-5-phosphate reductoisomerase (147 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Micrococcus luteus (7463 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter (437 Activities)

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Escherichia coli (133304 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Enterococcus faecalis (29875 Activities)

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Mycolicibacterium smegmatis (8003 Activities)

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Plasmodium falciparum (966862 Activities)

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Plasmodium berghei (192651 Activities)

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murD UDP-N-acetylmuramoylalanine--D-glutamate ligase (1 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase (191 Activities)

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Bacillus anthracis (2936 Activities)

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DXR 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic (3 Activities)

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rpmB 50S ribosomal protein L28 (2 Activities)

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rplB 50S ribosomal protein L2 (1 Activities)

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dapB 4-hydroxy-tetrahydrodipicolinate reductase (1 Activities)

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yefM Antitoxin YefM (1 Activities)

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ftsX Cell division protein FtsX (1 Activities)

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mreC Cell shape-determining protein MreC (1 Activities)

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hemA Glutamyl-tRNA reductase (1 Activities)

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glxK Glycerate kinase (1 Activities)

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cca Multifunctional CCA protein (2 Activities)

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fadL Outer membrane FadL protein (1 Activities)

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tolC Outer membrane protein TolC (10 Activities)

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mlaB Probable phospholipid ABC transporter-binding protein MlaB (1 Activities)

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lgt Prolipoprotein diacylglyceryl transferase (1 Activities)

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baeR Transcriptional regulatory protein BaeR (1 Activities)

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tsaE tRNA threonylcarbamoyladenosine biosynthesis protein TsaE (6 Activities)

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tilS tRNA(Ile)-lysidine synthase (1 Activities)

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ydfW Uncharacterized protein ydfW in Qin prophage region (1 Activities)

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ydiL Uncharacterized protein YdiL (3 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 183.100 g/mol
• XLogP3: -2.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 183.03 Da
• Monoisotopic Mass: 183.03 Da
• Topological Polar Surface Area: 98.100 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 166.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 66508-53-0, the molecular formula is C4H10NO5P, and the molecular weight is 183.1 g/mol. InChIKey GJXWDTUCERCKIX-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.