FPA 124 , CAS No.902779-59-3

CAS: 902779-59-3 Cat. No.: F287149 Formula: C₁₁H₉Cl₂CuN₃O₂S Peso molecolare: 381.73

Synonyms

Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifiche

Sinonimi

Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex

Meccanismi biochimici e fisiologici

Akt/PKB inhibitor (IC50= 100 nM) that interacts with the PH and kinase domains. Inhibits cell proliferation in various cancer cell linesin vitroand decreases NF-κB activity and tumor loadin vivo.

Condizioni di conservazione di stoccaggio

Store at 2-8°C

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nomi e identificatori

Sorrisi canonici

C1=CC=C2C(=C1)C(=O)C(=CO2)C=NNC(=S)N.Cl[Cu]Cl

IUPAC Name

dichlorocopper;[(Z)-(4-oxochromen-3-yl)methylideneamino]thiourea

InChIKey

HZRXQEVFXXQYFS-KHDHKOIVSA-L

INCHI

1S/C11H9N3O2S.2ClH.Cu/c12-11(17)14-13-5-7-6-16-9-4-2-1-3-8(9)10(7)15;;;/h1-6H,(H3,12,14,17);2*1H;/q;;;+2/p-2/b13-5-;;;

Isomeri SMILES

C1=CC=C2C(=C1)C(=O)C(=CO2)/C=N\NC(=S)N.Cl[Cu]Cl

Peso molecolare

381.73

Reaxy-Rn

33496790

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33496790&ln=

Proprietà chimiche e fisiche

• Solubilità: Solvent:DMSO, Max Conc. mg/mL: 3.82, Max Conc. mM: 10; Solvent:ethanol, Max Conc. mg/mL: 3.82, Max Conc. mM: 10

Domande frequenti

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 902779-59-3, the molecular formula is C11H9Cl2CuN3O2S, and the molecular weight is 381.73 g/mol. InChIKey HZRXQEVFXXQYFS-KHDHKOIVSA-L.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.