FPH1 (BRD-6125) - ≥95% , CAS No.708219-39-0

CAS: 708219-39-0 Cat. No.: F418548 Formula: C₁₆H₁₅ClF₂N₂O₃S Peso molecolare: 388.81 Numero EC: 806-114-4

GRADE & PURITY ≥95%

Synonyms

AKOS000376622 | CCG-268509 | AC-36148 | BRD6125 | BRD-6125 | SW220075-1 | FPH-1(BRD6125) | 2-(N-(5-Chloro-2-methylphenyl)methylsulfonamido)-N-(2,6-difluorophenyl)acetamide | s7451 | N~2~-(5-chloro-2-methylphenyl)-N-(2,6-difluorophenyl)-N~2~-(methylsulfony

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes.

FPH1(BRD-6125) increases the number and activity of primary human hepatocytes in vitro and promotes the differentiation of iPS cells towards a hepatic lineage

Specifications

Sinonimi

AKOS000376622 | CCG-268509 | AC-36148 | BRD6125 | BRD-6125 | SW220075-1 | FPH-1(BRD6125) | 2-(N-(5-Chloro-2-methylphenyl)methylsulfonamido)-N-(2,6-difluorophenyl)acetamide | s7451 | N~2~-(5-chloro-2-methylphenyl)-N-(2,6-difluorophenyl)-N~2~-(methylsulfony

Specifiche e purezza

≥95%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥95%

Nomi e identificatori

Pubchem Sid

528764481

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528764481

Sorrisi canonici

CC1=C(C=C(C=C1)Cl)N(CC(=O)NC2=C(C=CC=C2F)F)S(=O)(=O)C

IUPAC Name

2-(5-chloro-2-methyl-N-methylsulfonylanilino)-N-(2,6-difluorophenyl)acetamide

InChIKey

WAOBCCBUTHNTFO-UHFFFAOYSA-N

INCHI

1S/C16H15ClF2N2O3S/c1-10-6-7-11(17)8-14(10)21(25(2,23)24)9-15(22)20-16-12(18)4-3-5-13(16)19/h3-8H,9H2,1-2H3,(H,20,22)

Isomeri SMILES

CC1=C(C=C(C=C1)Cl)N(CC(=O)NC2=C(C=CC=C2F)F)S(=O)(=O)C

Peso molecolare

388.81

Reaxy-Rn

29246424

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29246424&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Sulfanilides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Sulfanilides
• Intermediate Tree Nodes: Not available
• Direct Parent: Sulfanilides
• Alternative Parents: Alpha amino acids and derivatives Anilides N-arylamides Toluenes Chlorobenzenes Fluorobenzenes Organosulfonamides Aryl chlorides Aryl fluorides Organic sulfonamides Aminosulfonyl compounds Secondary carboxylic acid amides Organofluorides Organopnictogen compounds Carbonyl compounds Hydrocarbon derivatives Organochlorides Organic oxides
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Alpha-amino acid or derivatives - Sulfanilide - Anilide - N-arylamide - Chlorobenzene - Fluorobenzene - Halobenzene - Toluene - Aryl fluoride - Organosulfonic acid amide - Organic sulfonic acid amide - Aryl halide - Aryl chloride - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Aminosulfonyl compound - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Hydrocarbon derivative - Organochloride - Organohalogen compound - Organofluoride - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organosulfur compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as sulfanilides. These are organic aromatic compounds containing a sulfanilide moiety, with the general structure RS(=O)(=O)NC1=CC=CC=C1.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (non umani)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: H2O:<1 mg/mL；DMSO:72 mg/mL (185.2 mM)；Ethanol:<1 mg/mL
• Peso molecolare: 388.800 g/mol
• XLogP3: 3.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 388.046 Da
• Monoisotopic Mass: 388.046 Da
• Topological Polar Surface Area: 74.900 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 562.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1