Gardiquimod - Moligand™, 10 mM in DMSO , CAS No.1020412-43-4

CAS: 1020412-43-4 Cat. No.: G1493721 Molecular Weight: 313.4 EC Number: 806-274-5

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Gardiquimod, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod specifically activates TLR7 when used at concentrations below 10 μM .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
• Molecular Weight: 313.4
• Reaxy-Rn: 19659786
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19659786&ln=

References

1. Xiaolong Li, Lanlan Ma, Jueshuo Guo, Yaya Wei, Shijie Ma, Yaping Mai, Guojing Gou, Wenbao Zuo, Jianhong Yang.  (2025)  Synergistic anti-tumor effects of mRNA vaccine and PERK inhibitor combination in melanoma treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:40383023] [10.1016/j.colsurfb.2025.114808]