GITR/CD357 Rat mAb (APC) - Anticorpo primario, specific to GITR/CD357, Rat IgG2b

Cat. No.: Ab190293

GRADE & PURITY Validated, ExactAb™, Ex:650nm, Em:660nm, 0.5 mg/mL

Application

Flow Cytometry

Host species

consiglio

Reactive species

Mouse

Isotype

Rat IgG2b

Clone Number

DTA-1

Conjugation

APC

Panoramica

Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow.

Specifications

Product Name

GITR/CD357 Rat mAb (APC) - Anticorpo primario, specific to GITR/CD357, Rat IgG2b

Sinonimi

Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein |

Specifiche e purezza

ExactAb™, Validated, Ex:650nm, Em:660nm, 0.5 mg/mL

Meccanismi biochimici e fisiologici

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Specie ospite

consiglio

Specificità

GITR/CD357

Immunogeno

Mouse CD25+ CD4+ T cells

Controllo positivo

Flow: C57BL/6 mouse splenocytes.

Coniugazione

APC

Eccitazione (nm)

Red Laser(633nm)

Emissione (nm)

660nm

Ex/Em(nm)

Ex:650nm;Em:660nm

Grado

Em:660nm, Ex:650nm, ExactAb™, Validated

Isotipo

Rat IgG2b

Tipo di catena leggera

lambda

Metodo di purificazione

Protein G purified

Concentrazione

0.5 mg/mL

Stoccaggio e spedizione

Condizioni di conservazione di stoccaggio

Store at 2-8°C,Protected from light,Do not freeze

Spedito in

Wet ice,Do not freeze

Stabilità e conservazione

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Immagini

Flow Cytometry: GITR/CD357 Rat mAb (APC) (Ab190293)

GITR/CD357 Rat mAb (APC) (Ab190293) - Flow Cytometry
Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (PE) (Ab179011) and either Rat IgG Isotype Control Antibody (APC) (Ab180313; Left panel) or GITR/CD357 Rat mAb (APC) (Ab190293; Right panel) at 1 μg/mL. Total viable cells were used for analysis.

Applicazione

• Applicazione: Dilution info
• Flow Cytometry:

  ≤0.3 μg/test, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume ;

Obiettivi associati (umani)

TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 (0 Activities)

Discover Target: TNFRSF18

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Meccanismi d'azione