Glucosamine - 10mM in DMSO , Supplement, CAS No.3416-24-8, Supplement

CAS: 3416-24-8 Cat. No.: G423487 Formula: C₆H₁₃NO₅ Peso molecolare: 179.17 Beilstein Registry Number: 1423209 Numero EC: 222-311-2

QUALITÀ & PUREZZA 10mM in DMSO

Synonyms

2-Amino-2-Deoxy-D-Glucopyranose|Glucosamine free base|2-Amino-2-Deoxy-D-Glucopyranoside|D-Glucose, 2-amino-2-deoxy-|methyl-3-(chlorosulfonyl)thiophene-2-carboxylate|(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-methyl-amine|2-Deoxy-2-Amino-Glucopyranose|D-GlcN|(+)-2-amino-2-deoxy-D-glucopyranose|Glucosaminum (INN-Latin)|GlcNH2|Glucosamine|Glucosamine [USAN:INN]|2-amino-2-deoxyglucose|2-Amino-2-Deoxy-Glucose|GlcN|glucosamin|Glucosamina [INN-Spanish]|2-Deoxy-2-aminoglucose|2-Deoxy-2-Amino-Glucose|WURCS=2.0/1,1,0/(a2122h-1x_1-5_2*N)/1/|2-Deoxy-2-Amino-Glucopyranoside|1-(4-Methoxyphenyl)-5-oxo-pyrrolidine-3-carboxylic acid|2-Amino-2-Deoxy-D-Glucose|2-Deoxy-2-Amino-D-Glucopyranose|D-Glucopyranose, 2-deoxy-2-Amino-|2-Deoxy-2-Amino-D-Glucose|(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol|2 Amino 2 Deoxyglucose|Glucosamine (USAN/INN)|2-Amino-2-Deoxy-Glucopyranose|chitosamine|Glucosamina|(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol|D-Glucosamine|2-Amino-2-deoxyhexopyranose #|Glucosamina (INN-Spanish)|Glucosaminum [INN-Latin]|Glucosaminum|2-Amino-2-Deoxy-Glucopyranoside|2-Aminoglucose

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Glucosamine Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.

Specifiche

Sinonimi

2-Amino-2-Deoxy-D-Glucopyranose | Glucosamine free base | 2-Amino-2-Deoxy-D-Glucopyranoside | D-Glucose, 2-amino-2-deoxy- | methyl-3-(chlorosulfonyl)thiophene-2-carboxylate | (1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-yl)-methyl-amine | 2-Deoxy-2-Amino-Glucopyranose | D-GlcN | (+)-2-amino-2-deoxy-D-glucopyranose | Glucosaminum (INN-Latin Mostra altro

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulate

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Meccanismo d'azione

Supplement

Proprietà del prodotto

pKa

pKₐ: 12.27 (Predicted), pKₐ: 8.44 (Predicted)

Nomi e identificatori

Pubchem Sid

528772573

Isomeri SMILES

C([C@@H]1[C@H]([C@@H]([C@H](C(O1)O)N)O)O)O

RTECS

LZ6665000

Peso molecolare

179.17

Beilstein

1423209

Reaxy-Rn

1423209

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1423209&ln=

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HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

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ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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MAOA Tclin Monoamine oxidase A (11911 Activities)

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DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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ACHE Tclin Acetylcholinesterase (18204 Activities)

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ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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OPRM1 Tclin Mu opioid receptor (19785 Activities)

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DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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SLC6A3 Tclin Dopamine transporter (10535 Activities)

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KCNH2 Tclin HERG (29587 Activities)

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PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

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PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

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ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

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HT-1080 (3966 Activities)

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MDA-MB-231 (73002 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Indice di rifrazione: n20D1.6 (Predicted)
• Punto di ebollizione (°C): ~449.9° C at 760 mmHg (Predicted)
• Punto di fusione (°C): 109-111° C
• Peso molecolare: 179.170 g/mol
• XLogP3: -2.800
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 179.079 Da
• Monoisotopic Mass: 179.079 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 155.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1