GSK1904529A - Moligand™, ≥98% , CAS No.1089283-49-7
Disponibile
SKU
G127237
Selective IGF-1R/IR tyrosine kinase inhibitor
GSK1904529A is a potent, selective, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.
Maggiori Informazioni
| CAS | 1089283-49-7 |
|---|---|
| Sinonimi | MOSKATHMXWSZTQ-UHFFFAOYSA-N | SB18897 | Trifluralin [ANSI:BSI:ISO] | AMY24202 | A24618 | GSK 4529 | IGF-1R inhibitor GS1904529A | MLS006010966 | N-(2,6-Difluorophenyl)-5-[3-[2-[[5-ethyl-2-(methyloxy)-4-[4-[4-(methylsulfonyl)-1-piperazinyl]-1-Piperidinyl]p |
| Specifiche e purezza | Moligand™, ≥98% |
| Condizioni di conservazione di stoccaggio | Store at -20°C |
| Spedito in | Ice chest + Ice pads |
| Product Description |
GSK1904529A is a potent, selective, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.
|
| Pubchem Sid | 504769975 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504769975 |
| Solubilità | DMSO 124 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| PubChem CID | 25124816 |
| Formula molecolare | C44H47F2N9O5S |
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