H-89 - Moligand™, 10 mM in DMSO , CAS No.127243-85-0

CAS: 127243-85-0 Cat. No.: H1498370 Molecular Weight: 446.36 EC Number: 675-767-3
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
H1498370-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$34.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase ( protein kinase A ) with IC 50 of 48 nM and has weak inhibition on PKG , PKC , Casein Kinase , and others kinases.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br
Alternate CAS 130964-39-5
Molecular Weight 446.36
Reaxy-Rn 8160271
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8160271&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Boil Point(°C)639.7ºC
Melt Point(°C)195-200°C
Citations of This Product
References
1. Yong Chang, Fengli Gao, Tong Wu, Qiuzhi Pan, Lin Liu, Qijun Song.  (2023)  Electrochemical detection of protein kinases with methylene blue-functionalized Zr-based metal-organic frameworks as signal labels.  International Journal of Electrochemical Science,      [PMID:] [10.1016/j.ijoes.2023.100338]
2. Yong Chang, Xiaohua Ma, Ting Sun, Lin Liu, Yuanqiang Hao.  (2021)  Electrochemical detection of kinase by converting homogeneous analysis into heterogeneous assay through avidin-biotin interaction.  TALANTA,      [PMID:34364458] [10.1016/j.talanta.2021.122649]
3. Zhiqiang Chen, Ying Liu, Lijie Hao, Zhencai Zhu, Fang Li, Shufeng Liu.  (2018)  Reduced Graphene Oxide-Zirconium Dioxide–Thionine Nanocomposite Integrating Recognition, Amplification, and Signaling for an Electrochemical Assay of Protein Kinase Activity and Inhibitor Screening.  ACS Applied Bio Materials,      [PMID:34996206] [10.1021/acsabm.8b00451]
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