H-89 - Moligand™, 10 mM in DMSO , CAS No.127243-85-0

CAS: 127243-85-0 Cat. No.: H1498370 Formula: C₂₀H₂₀BrN₃O₂S Peso molecolare: 446.36 Numero EC: 675-767-3

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase ( protein kinase A ) with IC 50 of 48 nM and has weak inhibition on PKG , PKC , Casein Kinase , and others kinases.

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Isomeri SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br
• CAS alternativo: 130964-39-5
• Peso molecolare: 446.36
• Reaxy-Rn: 8160271
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8160271&ln=

Proprietà chimiche e fisiche

• Punto di ebollizione (°C): 639.7ºC
• Punto di fusione (°C): 195-200°C

Riferimenti

1. Yong Chang, Fengli Gao, Tong Wu, Qiuzhi Pan, Lin Liu, Qijun Song.  (2023)  Electrochemical detection of protein kinases with methylene blue-functionalized Zr-based metal-organic frameworks as signal labels.  International Journal of Electrochemical Science,      [PMID:] [10.1016/j.ijoes.2023.100338]

2. Yong Chang, Xiaohua Ma, Ting Sun, Lin Liu, Yuanqiang Hao.  (2021)  Electrochemical detection of kinase by converting homogeneous analysis into heterogeneous assay through avidin-biotin interaction.  TALANTA,      [PMID:34364458] [10.1016/j.talanta.2021.122649]

3. Zhiqiang Chen, Ying Liu, Lijie Hao, Zhencai Zhu, Fang Li, Shufeng Liu.  (2018)  Reduced Graphene Oxide-Zirconium Dioxide–Thionine Nanocomposite Integrating Recognition, Amplification, and Signaling for an Electrochemical Assay of Protein Kinase Activity and Inhibitor Screening.  ACS Applied Bio Materials,      [PMID:34996206] [10.1021/acsabm.8b00451]

Domande frequenti

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 127243-85-0, the molecular formula is C20H20BrN3O2S, and the molecular weight is 446.36 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.