H3B-120 - 10mM in DMSO , CAS No.2194903-42-7

CAS: 2194903-42-7 Cat. No.: H422634 Formula: C19H24N4O2S Peso molecolare: 372.48
Disponibile su ordine
GRADE & PURITY 10mM in DMSO
Synonyms
N1-Methyl-N4-(4-methyl-2-thiazolyl)-N1-(phenylmethyl)-1,4-piperidinedicarboxamide
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
Germania (EU)
USA*
Price
Qty
1ml
H422634-1ml
—
2 Disponibile

131,81€

192,55€
Salva 60,74 € (31.55%)
Enter a quantity for the sizes you want to add.
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

Information

H3B-120 H3B-120 is a competitive, selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 1.5 μM and Ki of 1.4 μM. H3B-120 exhibits anti-tumor activity.

Targets

CPS1 (Cell-free assay); CPS1 (Cell-free assay) 1.4 μM(Ki); 1.5 μM

Specifications

Sinonimi
N1-Methyl-N4-(4-methyl-2-thiazolyl)-N1-(phenylmethyl)-1,4-piperidinedicarboxamide
Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
H3B-120 is a competitive, selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 1.5 μM and Ki of 1.4 μM. H3B-120 exhibits anti-tumor activity.
Condizioni di conservazione di stoccaggio
Protected from light,Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
INHIBITOR
Proprietà del prodotto
ALogP
1.901
hba_count
3
Conteggio HBD
1
Legame rotabile
4
Nomi e identificatori
Pubchem Sid
Sorrisi canonici
CC1=CSC(=N1)NC(=O)C2CCN(CC2)C(=O)N(C)CC3=CC=CC=C3
IUPAC Name
1-N-benzyl-1-N-methyl-4-N-(4-methyl-1,3-thiazol-2-yl)piperidine-1,4-dicarboxamide
InChIKey
ZEVOZXRSCSSPAO-UHFFFAOYSA-N
INCHI
1S/C19H24N4O2S/c1-14-13-26-18(20-14)21-17(24)16-8-10-23(11-9-16)19(25)22(2)12-15-6-4-3-5-7-15/h3-7,13,16H,8-12H2,1-2H3,(H,20,21,24)
Isomeri SMILES
CC1=CSC(=N1)NC(=O)C2CCN(CC2)C(=O)N(C)CC3=CC=CC=C3
Peso molecolare
372.48
Reaxy-Rn
35902200
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=35902200&ln=

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassePiperidines
SubclassPiperidinecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentPiperidinecarboxamides
Alternative Parents N-arylamides  2,4-disubstituted thiazoles  N-acyl amines  Benzene and substituted derivatives  Heteroaromatic compounds  Ureas  Sulfenyl compounds  Propargyl-type 1,3-dipolar organic compounds  Carboxylic acid amides  Carboximidamides  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Piperidinecarboxamide - 1-piperidinecarboxamide - N-arylamide - 2,4-disubstituted 1,3-thiazole - Benzenoid - N-acyl-amine - Monocyclic benzene moiety - Heteroaromatic compound - Thiazole - Azole - Urea - Carbonic acid derivative - Carboxamide group - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Sulfenyl compound - Carboximidamide - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
DescrizioneThis compound belongs to the class of organic compounds known as piperidinecarboxamides. These are compounds containing a piperidine ring substituted with a carboxamide functional group.
External Descriptors Not available
Struttura 3D
Modello di struttura chimica interattiva





Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDataOggetto
F2417499Certificate of AnalysisMay 11, 2026 H422634
Proprietà chimiche e fisiche
SensibilitàLight sensitive
DMSO (mg/mL) Solubilità massima74
DMSO (mM) Solubilità massima198.668384879725
Acqua (mg/mL) Solubilità massima<1
Peso molecolare372.500 g/mol
XLogP32.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass372.162 Da
Monoisotopic Mass372.162 Da
Topological Polar Surface Area93.800 Ų
Heavy Atom Count26
Formal Charge0
Complexity490.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calcolatori di soluzioni
Recensioni

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