HDAC3 Mouse mAb - Anticorpo primario, specific to HDAC3, Mouse IgG1

Cat. No.: Ab107045
Disponibile su ordine
QUALITÀ & PUREZZA ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. 2.9 mg/mL
Application
WB
Host species
Mouse
Reactive species
consiglio, Mouse, Umano
Isotype
Mouse IgG1
Clone Number
3G3-H6-H10
Conjugation
Unconjugated
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Dimensione
Germania (EU)
USA*
Prezzo
Qtà
10μl
Ab107045-10μl
Su ordinazione · 8–12 settimane
86,69€
50μl
Ab107045-50μl
—
1 Disponibile
225,53€
100μl
Ab107045-100μl
Su ordinazione · 8–12 settimane
364,36€
1ml
Ab107045-1ml
Su ordinazione · 8–12 settimane
2.950,23€
Enter a quantity for the sizes you want to add.
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Perché questa qualità

ExactAb™, Validated, 2.9 mg/mL ExactAb™,Validated per flussi di lavoro cromatografici e analitici sensibili che richiedono un'interferenza minima della linea di base.

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Stoccaggio e spedizione

Store at -20°C,Avoid repeated freezing and thawing Spedizione Ice chest + Ice pads. Consultare il COA specifico del lotto per le specifiche esatte.

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Documenti di qualità

SDS, COA, scheda tecnica e scheda delle specifiche disponibili per il download. COA specifico del lotto accessibile tramite ricerca per numero di lotto.

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Prova documentale

Citato in 0 pubblicazioni peer-reviewed su cromatografia, sintesi organica e reazioni di accoppiamento incrociato.

Panoramica

Mouse anti Human HDAC3 Antibody, Monoclonal (3G3-H6-H10), could be used for WB and so on.

Application:

WB: 1/500-1/1000

Protein Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.

Specifiche

Product Name
HDAC3 Mouse mAb - Anticorpo primario, specific to HDAC3, Mouse IgG1
Sinonimi
HD3 antibody | HDAC 3 antibody | HDAC3 antibody | HDAC3_HUMAN antibody | Histone deacetylase 3 antibody | RPD3 2 antibody | RPD3 antibody | RPD3-2 antibody | SMAP45 antibody | HDAC3 | HD3 | RPD3 | KDAC3 | RPD3-2 | EC 3.5.1.98 | HD3 | RPD3-2 | SMAP45
Specifiche e purezza
ExactAb™, Validated, 2.9 mg/mL
Specie ospite
Mouse
Specificità
HDAC3
Immunogeno
Purified recombinant human HDAC3 protein fragments expressed in E.coli (AA 216-422).
Controllo positivo
WB: C6, NIH/3T3, HEK293, LNCaP, K562 and HeLa cell lysates.
Coniugazione
Unconjugated
Grado
ExactAb™, Validated
Isotipo
Mouse IgG1
Tipo di catena leggera
kappa
SDS-PAGE
150 kDa
Metodo di purificazione
Protein G purified
Concentrazione
2.9 mg/mL
Product Line
Prodotti biologici
Stoccaggio e spedizione
Forma
Liquid
Condizioni di conservazione di stoccaggio
Store at -20°C,Avoid repeated freezing and thawing
Spedito in
Ice chest + Ice pads
Stabilità e conservazione
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Immagini

HDAC3 Mouse mAb (Ab107045) - Western Blot
All lanes: HDAC3 Mouse mAb (Ab107045) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/30000 dilution

Predicted band size: 49 kDa
Observed band size: 47 kDa
Exposure time: 209.7 s

Applicazione
Applicazione
Dilution info
WB

1/500-1/1000

Documentazione

📋 Scheda di dati di sicurezza (SDS)

Documento completo su pericoli, manipolazione, stoccaggio e conformità normativa.

<<<<<<< HEAD Scarica SDS → ======= Scarica SDS → >>>>>>> release248-p3

✅ Certificato di analisi (COA)

Dati di qualità specifici del lotto. Inserisci il numero di lotto per recuperare il COA esatto.

Cerca COA →

📊 Scheda tecnica

Riepilogo di riferimento rapido delle specifiche e applicazioni del prodotto.

Visualizza scheda tecnica →

🔬 Scheda delle specifiche

Attributi di qualità completi e criteri di accettazione per questa qualità.

Visualizza scheda delle specifiche →

Dati avanzati

Obiettivi associati (umani)
HDAC3 Tclin Histone deacetylase 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC3 Tclin Histone deacetylase 3 (3654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC3 Tclin Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (735 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC3 Tclin Histone deacetylase 3/NCoR1 (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC3 Tclin Histone deacetylase 6/3 (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC3 Tclin Protein cereblon/Histone deacetylase 3 (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDataOggetto
ZJ23F1202108ZJ23F1202108Certificate of AnalysisDec 20, 2023 Ab107045
ZJ23F1202107ZJ23F1202107Certificate of AnalysisDec 20, 2023 Ab107045
Domande frequenti e articoli
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

Domande frequenti

What does ExactAb? mean?
ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.
What does Validated mean?
Validated indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.
How should this product be stored?
Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Which species reactivity has this antibody been validated against?
Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (HDAC3 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.

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