HNHA - Moligand™, ≥98% , CAS No.926908-04-5

CAS: 926908-04-5 Cat. No.: H274734 Formula: C₁₇H₂₁NO₂S Peso molecolare: 303.42

GRADE & PURITY Moligand™, ≥98%

Synonyms

BMB90804 | GTPL7911 | HY-118672 | CCG-208687 | CHEBI:94741 | N-hydroxy-7-(naphthalen-2-ylthio)heptanamide | AS-66085 | D83880 | SCHEMBL17141115 | AKOS016371022 | Q27077989 | Histone Deacetylase Inhibitor VI, HNHA | N-Hydroxy-7-[(naphthalen-2-yl)sulfanyl]h

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Store at -20°C.

Specifications

Sinonimi

BMB90804 | GTPL7911 | HY-118672 | CCG-208687 | CHEBI:94741 | N-hydroxy-7-(naphthalen-2-ylthio)heptanamide | AS-66085 | D83880 | SCHEMBL17141115 | AKOS016371022 | Q27077989 | Histone Deacetylase Inhibitor VI, HNHA | N-Hydroxy-7-[(naphthalen-2-yl)sulfanyl]h

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

Potent, cell-permeable HDAC inhibitor (IC 50 = 100 nM). Induces histone hyperacetylation and p21 transcription with concomitant inhibition of cell cycle progression. Arrests cell cycle at G 1 /S phase in cancer cells. Antitumor and antiangiogenic agent.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: C1=CC=C2C=C(C=CC2=C1)SCCCCCCC(=O)NO
• IUPAC Name: N-hydroxy-7-naphthalen-2-ylsulfanylheptanamide
• InChIKey: KPNNXHVGOKRBEF-UHFFFAOYSA-N
• INCHI: 1S/C17H21NO2S/c19-17(18-20)9-3-1-2-6-12-21-16-11-10-14-7-4-5-8-15(14)13-16/h4-5,7-8,10-11,13,20H,1-3,6,9,12H2,(H,18,19)
• Isomeri SMILES: C1=CC=C2C=C(C=CC2=C1)SCCCCCCC(=O)NO
• Peso molecolare: 303.42
• Reaxy-Rn: 25966830
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25966830&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Naphthalenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Naphthalenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthalenes
• Alternative Parents: Thiophenol ethers Alkylarylthioethers Hydroxamic acids Sulfenyl compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Naphthalene - Thiophenol ether - Aryl thioether - Alkylarylthioether - Hydroxamic acid - Sulfenyl compound - Thioether - Carboxylic acid derivative - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxygen compound - Carbonyl group - Aromatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Soluble in DMSO to 100 mM
• Peso molecolare: 303.400 g/mol
• XLogP3: 4.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 303.129 Da
• Monoisotopic Mass: 303.129 Da
• Topological Polar Surface Area: 74.600 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 311.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 926908-04-5, the molecular formula is C17H21NO2S, and the molecular weight is 303.42 g/mol. InChIKey KPNNXHVGOKRBEF-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.