HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K + channels, and blocks extracellular Ca 2+ influx.
In Vitro
HUP30 inhibits Phenylephrine-induced aorta contraction with an IC 50 value of 3.9 μM. HUP30 (100 μM) increases cGMP levels in Phenylephrine-stimulated aorta. HUP30 causes an antispasmodic effect on rat aorta rings contracted by 25/30 mM K + , with an IC 50 value of 7.5 μM. HUP30 (3-100 μM) inhibits both extracellular Ca 2+ influx and Ca 2+ mobilization induced by Phenylephrine. HUP30 (10-100 μM) inhibits the current in single tail artery myocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifiche
Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K + channels, and blocks extracellular Ca 2+ influx.
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
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Tipo di azione
INHIBITOR
Nomi e identificatori
Isomeri SMILES
C1CCC(CC1)C(=O)NC2=NC3=C(S2)C=C(C=C3)[N+](=O)[O-]
WGK Germania
3
PubChem CID
739510
Peso molecolare
305.35
Dati avanzati
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
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Recensioni
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Domande frequenti
How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 312747-21-0, the molecular formula is C14H15N3O3S, and the molecular weight is 305.35 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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