INDY - ≥98% , CAS No.1169755-45-6

CAS: 1169755-45-6 Cat. No.: I275280 Formula: C₁₂H₁₃NO₂S Peso molecolare: 235.3

GRADE & PURITY ≥98%

Synonyms

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Shipped at Room Temperature. Store at +4°C short term (1-2 weeks). Store at -20°C.

Specifications

Sinonimi

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Potent DYRK1A/B inhibitor (IC 50 values are 0.23 and 0.24\xa0µM for DYRK1B and DYRK1A respectively). Also inhibits DYRK2, DTRK4, CLK1, CLK4, casein kinase 1 and PIM1 (> 90% inhibition at 10 μM).

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 488202143
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488202143
• Sorrisi canonici: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• IUPAC Name: 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one
• InChIKey: GCSZJMUFYOAHFY-UHFFFAOYSA-N
• INCHI: 1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3
• Isomeri SMILES: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• Peso molecolare: 235.3
• Reaxy-Rn: 28418243
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28418243&ln=

Proprietà chimiche e fisiche

• Solubilità: Soluble in DMSO to 100 mM