IQ-1S - ≥98% , CAS No.23146-22-7

CAS: 23146-22-7 Cat. No.: I275973 Formula: C₁₅H₉N₃O Peso molecolare: 247.25 PubChem CID: 619002

GRADE & PURITY ≥98%

Synonyms

11H-Indeno[1,2-b]quinoxalin-11-oneoxime

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Store at Room Temperature. The product can be stored for up to 12 months.

Specifications

Sinonimi

11H-Indeno[1,2-b]quinoxalin-11-oneoxime

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Selective JNK3 inhibitor (IC 50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo.

Fonte

Synthetic

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 504759563
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504759563
• Sorrisi canonici: C1=CC=C2C(=C1)C(=C3C2=NC4=CC=CC=C4N3)N=O
• IUPAC Name: 11-nitroso-10H-indeno[1,2-b]quinoxaline
• InChIKey: YSYIWCNPSZNNKW-UHFFFAOYSA-N
• INCHI: 1S/C15H9N3O/c19-18-14-10-6-2-1-5-9(10)13-15(14)17-12-8-4-3-7-11(12)16-13/h1-8,17H
• Isomeri SMILES: C1=CC=C2C(=C1)C(=C3C2=NC4=CC=CC=C4N3)N=O
• PubChem CID: 619002
• Peso molecolare: 247.25

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Diazanaphthalenes
      • Subclass Benzodiazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoxalines
• Alternative Parents: Pyrazines Benzenoids Heteroaromatic compounds Propargyl-type 1,3-dipolar organic compounds C-nitroso compounds Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoxaline - Pyrazine - Benzenoid - Heteroaromatic compound - C-nitroso compound - Organic nitroso compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Azacycle - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as quinoxalines. These are compounds containing a quinoxaline moiety, a bicyclic heterocycle made up of a benzene ring fused to a pyrazine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Soluble in DMSO to 5 mM
• Sensibilità: Moisture Sensitive；Light sensitive
• Punto di fusione (°C): 262 °C
• Peso molecolare: 247.250 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 247.075 Da
• Monoisotopic Mass: 247.075 Da
• Topological Polar Surface Area: 58.100 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 361.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 23146-22-7, the molecular formula is C15H9N3O, and the molecular weight is 247.25 g/mol. InChIKey YSYIWCNPSZNNKW-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.