Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer.
| Isomeri SMILES | CC1(C2=CC=CC=C2[N+](=C1C=CC3=C(C(=CC=C4C(C5=CC=CC=C5N4CCCCS(=O)(=O)[O-])(C)C)CCC3)Cl)CCCCS(=O)(=O)[O-])C.[Na+] |
|---|---|
| Peso molecolare | 749.35 |
| Reaxy-Rn | 14503446 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14503446&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Punto di fusione (°C) | 212 °C |
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| 1. Xiaoxia Wu, Dinghu Zhang, Ting Pan, Jianwei Li, Yujiao Xie, Chenguang Zhang, Chunshu Pan, Zhewei Zhang, Jie Lin, Aiguo Wu, Guoliang Shao. (2023) Stimuli-Responsive Codelivery System Self-Assembled from in Situ Dynamic Covalent Reaction of Macrocyclic Disulfides for Cancer Magnetic Resonance Imaging and Chemotherapy. ACS Applied Materials & Interfaces, [PMID:37721368] [10.1021/acsami.3c10245] |
| 2. Mingzhi Zhu, Pei Wang, Biaoqi Chen, Linrong Shi, Ruimin Long, Shibin Wang, Yuangang Liu. (2023) Active-oxygenating hollow Prussian blue nanosystems loaded with biomacromolecules for photodynamic/photothermal therapy of cancer and alleviating hypoxic tumors. MATERIALS & DESIGN, [PMID:] [10.1016/j.matdes.2023.112618] |
| 3. Wei Zhang, Yibao Fan, Jinze Zhang, Dan Shi, Jiahui Yuan, Milad Ashrafizadeh, Wei Li, Man Hu, A.M. Abd El-Aty, Ahmet Hacimuftuoglu, Michael Linnebacher, Yongxian Cheng, Weiguang Li, Shuo Fang, Peng Gong, Xianbin Zhang. (2023) Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer. DRUG RESISTANCE UPDATES, [PMID:37647746] [10.1016/j.drup.2023.101005] |
| 4. Jiaqi Zhou, Hao Li, Hui Li, Jiayi Ding, Zhong Du, Jiabao Xiong, Hongyang Yao, Xueliang Zhang, Nuernisha Alifu, Biao Dong. (2025) Constructing J-aggregates of Cyanine Dye for NIR-II in vivo Dynamic Vascular Imaging and Long-Term Targeting of Tumors. Materials Today Bio, [PMID:40242486] [10.1016/j.mtbio.2025.101693] |
| 5. Man Zhang, Ke Li, Junhao Kou, Guozhi Lu, Ling Qiu, Chunzhao Yang, Yongchun Liu, Qi Xue, Peng Yang. (2024) Functionalized Amyloid-Like Protein Nanofilm-Mediated Synergistic Disulfidptosis and Photodynamic Therapy for Preventing Postoperative Recurrence of Colorectal Cancer. Small Science, [PMID:] [10.1002/smsc.202400323] |
| 6. Wenrun Li, Li Shen, Shiyan Fu, Yong Li, Feng Huang, Qi Li, Qinyang Lin, Hongjia Liu, Qiuchi Wang, Liyi Chen, Huanhuan Tan, Juan Li, Yazhen Zhao, Yonghong Ran, Yuhui Hao. (2024) Mitochondrial-Targeting Mesoporous Polydopamine Nanoparticles for Reducing Kidney Injury Caused by Depleted Uranium. Advanced Healthcare Materials, [PMID:39543790] [10.1002/adhm.202403015] |
| 7. Fan Yibao, Zhang Wei, Iqbal Zoya, Li Xinxin, Lin Zhiyin, Wu Zhuolin, Li Qianyou, Dong Hongxia, Zhang Xianbin, Gong Peng, Liu Peng. (2024) Rod-shaped mesoporous silica nanoparticles reduce bufalin cardiotoxicity and inhibit colon cancer by blocking lipophagy. Lipids in Health and Disease, 23 (1): (1-12). [PMID:39334257] [10.1186/s12944-024-02301-y] |
| 8. Wu Xiao-Xia, Zhang Ding-Hu, Ding Yi-Nan, Cao Fei, Li Yang, Yao Jun-Lie, Miao Xin-Yu, He Lu-Lu, Luo Jun, Li Jian-Wei, Lin Jie, Wu Ai-Guo, Zheng Jia-Ping. (2024) Self-assembled co-delivery system of gold nanoparticles and paclitaxel based on in-situ dynamic covalent chemistry for synergistic chemo-photothermal therapy. RARE METALS, 44 (1): (417-429). [PMID:] [10.1007/s12598-024-03047-3] |
| 9. Man Zhang, Junhao Kou, Zhenyi Song, Ling Qiu, Chunzhao Yang, Qi Xue. (2025) A Janus Amyloid-like Nanofilm Inhibits Colorectal Cancer Postoperative Recurrence and Abdominal Adhesion via Synergistic Enzyme Cascade. Nanomaterials, 15 (9): (670). [PMID:40358287] [10.3390/nano15090670] |
| 10. Weijie Wang, Chenguang Sun, Linhao Jing, Yaning Xia, Shuijun Zhang, Yupeng Shi. (2025) Light-driven secondary structural remodeling in biomimetic nanosystem to enhance tumor chemo-phototherapy. Materials Today Bio, [PMID:40538753] [10.1016/j.mtbio.2025.101955] |
| 11. Chenchen Nie, Shanshu Yan, Gaoyuan Xing, Kaixin Ji, Xing Yang, Jianfeng Tang, Jiucun Chen, Yanan Zhao, Jie Hu, Jing Liu. (2026) In vivo detection of reactive oxygen species using turn-on luminescent probes based on IR783-modified upconversion nanoparticles. JOURNAL OF LUMINESCENCE, [PMID:] [10.1016/j.jlumin.2026.122086] |
| 12. Zhang Jieke, Li Yafang, Tian Chaoying, Zhang Xiaodi, Guo Jialing, Liu Chenxin, Wu Ligang, Du Bin, Cheng Genyang. (2026) Multifunctional Polydopamine Nanoparticles to Alleviate Oxidative Stress and Inhibit Ferroptosis for Cisplatin-Induced Acute Kidney Injury Therapy. MOLECULAR PHARMACEUTICS, 23 (8): (4341-4359). [PMID:42435348] [10.1021/acs.molpharmaceut.6c00719] |
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