JAK-IN-25 , CAS No.2127110-22-7

CAS: 2127110-22-7 Cat. No.: J646128 Formula: C19H17N5O4 Peso molecolare: 379.37
Disponibile su ordine
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Germania (EU)
USA*
Price
Qty
5mg
J646128-5mg
Su ordinazione · 8–12 settimane
365,23€
10mg
J646128-10mg
Su ordinazione · 8–12 settimane
590,84€
25mg
J646128-25mg
Su ordinazione · 8–12 settimane
1.180,91€
50mg
J646128-50mg
Su ordinazione · 8–12 settimane
1.909,81€
Enter a quantity for the sizes you want to add.
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

JAK-IN-25 (compound 19) is a potent JAK inhibitor with IC 50 s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2 , JAK1 , JAK2 , JAK3 , respectively. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC 50 of 28 nM. JAK-IN-25 has the potential for cancer research

Form:Solid

IC50& Target:Tyk2 6 nM (IC 50 ) JAK1 21 nM (IC 50 ) JAK2 8 nM (IC 50 ) JAK3 1051 nM (IC 50 )

Specifications

Meccanismi biochimici e fisiologici
JAK-IN-25 (compound 19) is a potent JAK inhibitor with IC 50 s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2 , JAK1 , JAK2 , JAK3 , respectively. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC 50 of 28 nM. JAK-IN-25 has the potential for cance
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
INHIBITOR
Nomi e identificatori
Peso molecolare
379.37

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Proprietà chimiche e fisiche
SolubilitàDMSO : 5 mg/mL (13.18 mM; ultrasonic and warming and heat to 60°C)
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

Domande frequenti

How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2127110-22-7, the molecular formula is C19H17N5O4, and the molecular weight is 379.37 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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