JNJ DGAT2-A - ≥98% , CAS No.1962931-71-0

CAS: 1962931-71-0 Cat. No.: J287704 Formula: C₂₄H₁₆BrFN₄O₂S Peso molecolare: 523.38 PubChem CID: 137025390

GRADE & PURITY ≥98%

Synonyms

3-Bromo-4-[2-fluoro-4-[[4-oxo-2-[[2-(pyridin-2-yl)ethyl]amino]-1,3-thiazol-5-(4H)ylidene]methyl]phenoxy]benzonitrile

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Product Describtion:

JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis.

Specifications

Sinonimi

3-Bromo-4-[2-fluoro-4-[[4-oxo-2-[[2-(pyridin-2-yl)ethyl]amino]-1,3-thiazol-5-(4H)ylidene]methyl]phenoxy]benzonitrile

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

DGAT2 inhibitor (IC50= 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 528764996
• Sorrisi canonici: C1=CC=NC(=C1)CCN=C2NC(=O)C(=CC3=CC(=C(C=C3)OC4=C(C=C(C=C4)C#N)Br)F)S2
• IUPAC Name: 3-bromo-4-[2-fluoro-4-[(Z)-[4-oxo-2-(2-pyridin-2-ylethylimino)-1,3-thiazolidin-5-ylidene]methyl]phenoxy]benzonitrile
• InChIKey: ZFRHAMOJHTZHLT-XKZIYDEJSA-N
• INCHI: 1S/C24H16BrFN4O2S/c25-18-11-16(14-27)5-6-20(18)32-21-7-4-15(12-19(21)26)13-22-23(31)30-24(33-22)29-10-8-17-3-1-2-9-28-17/h1-7,9,11-13H,8,10H2,(H,29,30,31)/b22-13-
• PubChem CID: 137025390
• Peso molecolare: 523.38

Proprietà chimiche e fisiche

• Solubilità: Solvent:DMSO, Max Conc. mg/mL: 52.34, Max Conc. mM: 100
• Sensibilità: light & Moisture sensitive