KY19382 (A3051) - ≥98% , CAS No.2226664-93-1

CAS: 2226664-93-1 Cat. No.: K413407 Formula: C₁₇H₁₁Cl₂N₃O₂ Peso molecolare: 360.19 PubChem CID: 148959784

GRADE & PURITY ≥98%

Synonyms

2H-​Indol-​2-​one,5,​6-​dichloro-​3-​[1,​3-​dihydro-​3-​(methoxyimino)​-​2H-​indol-​2-​ylidene]​-​1,​3-​dihydro-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Information

KY19382 (A3051) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β with IC50 of 19 nM and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity.

Specifications

Sinonimi

2H-​Indol-​2-​one,5,​6-​dichloro-​3-​[1,​3-​dihydro-​3-​(methoxyimino)​-​2H-​indol-​2-​ylidene]​-​1,​3-​dihydro-

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

KY19382 (A3051) is a Wnt/β-catenin signalling activator through inhibitory effects on both CXXC5–DVL interaction and GSK3β activity with IC50s of 19 nM and 10 nM, respectively.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

504773638

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504773638

Sorrisi canonici

CON=C1C2=CC=CC=C2N=C1C3=C(NC4=CC(=C(C=C43)Cl)Cl)O

IUPAC Name

5,6-dichloro-3-[(3Z)-3-methoxyiminoindol-2-yl]-1H-indol-2-ol

InChIKey

TVZDUDDLASVAOM-JCMHNJIXSA-N

INCHI

1S/C17H11Cl2N3O2/c1-24-22-15-8-4-2-3-5-12(8)20-16(15)14-9-6-10(18)11(19)7-13(9)21-17(14)23/h2-7,21,23H,1H3/b22-15-

PubChem CID

148959784

Peso molecolare

360.19

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2226664-93-1, the molecular formula is C17H11Cl2N3O2, and the molecular weight is 360.19 g/mol. InChIKey TVZDUDDLASVAOM-JCMHNJIXSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.