L-690330 hydrate , CAS No.L659295

CAS: L659295 Cat. No.: L659295 Molecular Weight: 316.14

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with K i s of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 1

Appearance:Solid

In Vitro:L-690330 hydrate (50 μM; 1 hour) induces P-AMPK and autophagy and increases LC3-I/II and p-AMPK expression in HEK293 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:L-690330 hydrate (intracerebroventricular injection; 0.1 μmol) has no effects on their motor activity and coordination in the beam walking, except a reduction in time spent in light in the dark/light test. MCE has not independently confirmed the accu

Biological Activity:L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with K i s of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 1

Specifications

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: OC1=CC=C(OC(P(O)(O)=O)(P(O)(O)=O)C)C=C1.O
• Molecular Weight: 316.14

Chemical and Physical Properties

• Solubility: DMSO : 31 mg/mL (98.06 mM; Need ultrasonic and warming) H2O : 31 mg/mL (98.06 mM; Need ultrasonic and warming)