L-Arginine - PharmPure™, USP, ChP, JP, Ph.Eur. , CAS No.74-79-3

CAS: 74-79-3 Cat. No.: GMP1526344 Formula: C₆H₁₄N₄O₂ Peso molecolare: 174.20 g/mol Beilstein Registry Number: 1725413 Numero EC: 200-811-1

GRADE & PURITY PharmPure™, USP, ChP, JP, Ph.Eur.

Storage

Protected from light,Room temperature,Argon charged

Shipped In

Normal

Panoramica

L-Arginine is an essential amino acid and precursor of nitric oxide synthesis that induces vasodilation in vivo. Nitric oxide potentiates insulin-mediated glucose uptake through the increase in blood flow.
A precursor of nitric oxide synthesis that induces vasodilation

Application：

L-Arginine has been used:
as a Roswell park memorial institute medium (RPMI) media component in the isolation and culture of peripheral blood mononuclear cells (PBMCs)
as a RPMI media component for tissue culture
in DMEM medium for the identification and quantification of phosphorylation sites by stable isotope labeling by amino acids in cell culture (SILAC) and LCMS/MS

Specifications

Specifiche e purezza

PharmPure™, USP, ChP, JP, Ph.Eur.

Meccanismi biochimici e fisiologici

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.Precursor to nitric oxide synthesis. Amino acid implicated in neurotransmission, immune defences and

Condizioni di conservazione di stoccaggio

Protected from light,Room temperature,Argon charged

Spedito in

Normal

Grado

ChP, JP, Ph.Eur., PharmPure™, USP

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nomi e identificatori

Sorrisi canonici

C(CC(C(=O)O)N)CN=C(N)N

IUPAC Name

(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid

InChIKey

ODKSFYDXXFIFQN-BYPYZUCNSA-N

INCHI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

Isomeri SMILES

C(C[C@@H](C(=O)O)N)CN=C(N)N

WGK Germania

1

RTECS

CF1934200

Peso molecolare

174.20 g/mol

Beilstein

1725413

Reaxy-Rn

2090768

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2090768&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Fatty acids and conjugates Guanidines Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidamides Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Fatty acid - Guanidine - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Amine - Hydrocarbon derivative - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Primary aliphatic amine - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Common amino acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Soluble in water (50 mg/ml), and alcohol (sparingly). Insoluble in ether.,
• Sensibilità: Air sensitive
• Rotazione specifica [α]: 27 ° (C=8, 6mol/L HCl)
• Punto di fusione (°C): 222 °C
• Peso molecolare: 174.200 g/mol
• XLogP3: -4.200
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 174.112 Da
• Monoisotopic Mass: 174.112 Da
• Topological Polar Surface Area: 128.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 176.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1