Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
A keto analogue of lactose.
| ALogP | -4.3 |
|---|
| Canonical Smiles | C(C1C(C(C(C(O1)OC2C(OC(C2O)(CO)O)CO)O)O)O)O |
|---|---|
| IUPAC Name | (2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| InChIKey | JCQLYHFGKNRPGE-FCVZTGTOSA-N |
| INCHI | 1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12-/m1/s1 |
| Isomeric SMILES | C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@@]([C@H]2O)(CO)O)CO)O)O)O)O |
| WGK Germany | 2 |
| RTECS | LS6965000 |
| Molecular Weight | 342.3 |
| Beilstein | 93773 |
| Reaxy-Rn | 19197061 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19197061&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbohydrates and carbohydrate conjugates |
| Intermediate Tree Nodes | Glycosyl compounds |
| Direct Parent | O-glycosyl compounds |
| Alternative Parents | Disaccharides C-glycosyl compounds Oxanes Tetrahydrofurans Secondary alcohols Hemiacetals Polyols Oxacyclic compounds Acetals Primary alcohols Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | O-glycosyl compound - Disaccharide - C-glycosyl compound - Oxane - Tetrahydrofuran - Secondary alcohol - Hemiacetal - Oxacycle - Organoheterocyclic compound - Polyol - Acetal - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond. |
| External Descriptors | glycosylfructose |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 04, 2026 | L104550 | |
| Certificate of Analysis | Feb 04, 2026 | L104550 | |
| Certificate of Analysis | Dec 03, 2025 | L104550 | |
| Certificate of Analysis | Dec 03, 2025 | L104550 | |
| Certificate of Analysis | Dec 03, 2025 | L104550 | |
| Certificate of Analysis | Dec 03, 2025 | L104550 | |
| Certificate of Analysis | Dec 03, 2025 | L104550 | |
| Certificate of Analysis | Aug 27, 2025 | L104550 | |
| Certificate of Analysis | Sep 13, 2024 | L104550 | |
| Certificate of Analysis | Sep 13, 2024 | L104550 | |
| Certificate of Analysis | Sep 13, 2024 | L104550 | |
| Certificate of Analysis | Sep 13, 2024 | L104550 | |
| Certificate of Analysis | Sep 13, 2024 | L104550 | |
| Certificate of Analysis | Nov 04, 2022 | L104550 | |
| Certificate of Analysis | Mar 27, 2022 | L104550 | |
| Certificate of Analysis | Mar 27, 2022 | L104550 | |
| Certificate of Analysis | Mar 27, 2022 | L104550 | |
| Certificate of Analysis | Mar 27, 2022 | L104550 |
| Solubility | Soluble in water (76.4%) at 30 °C, water (81%) at 60 °C, and water (>86%) at 90 °C. |
|---|---|
| Sensitivity | Hygroscopic |
| Refractive Index | 1.45-1.47 |
| Melt Point(°C) | ~169 °C (dec.) |
| Molecular Weight | 342.300 g/mol |
| XLogP3 | -4.300 |
| Hydrogen Bond Donor Count | 8 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 5 |
| Exact Mass | 342.116 Da |
| Monoisotopic Mass | 342.116 Da |
| Topological Polar Surface Area | 190.000 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 395.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Wang Pei, Wu Peng-Fei, Wang Hua-Jie, Liao Fang, Wang Fang, Chen Jian-Guo. (2023) Gut microbiome-derived ammonia modulates stress vulnerability in the host. Nature Metabolism, [PMID:37872351] [10.1038/s42255-023-00909-5] |
| 2. Min Kou, Young-Ho Oh, Sungyul Lee, Xianglei Kong. (2023) Distinguishing gas phase lactose and lactulose complexed with sodiated L-arginine by IRMPD spectroscopy and DFT calculations. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 25 (37): (25116-25121). [PMID:37676638] [10.1039/D3CP03406B] |
| 3. Jia Dong-Xu, Yu Hai, Wang Fan, Jin Li-Qun, Liu Zhi-Qiang, Zheng Yu-Guo. (2023) Computer-aided design of novel cellobiose 2-epimerase for efficient synthesis of lactulose using lactose. BIOPROCESS AND BIOSYSTEMS ENGINEERING, [PMID:37450268] [10.1007/s00449-023-02896-z] |
| 4. Yujin Wang, Hua Jiang, Lijun Wang, Huiping Gan, Xinchun Xiao, Liangwu Huang, Wenxin Li, Zongrun Li. (2023) Arctiin alleviates functional constipation by enhancing intestinal motility in mice. Experimental and Therapeutic Medicine, 25 (5): (1-10). [PMID:37090075] [10.3892/etm.2023.11898] |
| 5. Wang Yujin, Jiang Hua, Wang Lijun, Gan Huiping, Xiao Xinchun, Huang Liangwu, Li Wenxin, Li Zongrun. (2023) Luteolin ameliorates loperamide-induced functional constipation in mice. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, [PMID:36722660] [10.1590/1414-431X2023e12466] |
| 6. Pengfei Guan, Chengyi Xie, Lei Li, Xiangyu Fang, Fangling Wu, Jun Jack Hu, Keqi Tang. (2021) Structural resolution of disaccharides through halogen anion complexation using negative trapped ion mobility spectrometry. TALANTA, [PMID:33934797] [10.1016/j.talanta.2021.122348] |
| 7. Lei Li, Jiancheng Yu, Chengyi Xie, Chenlu Wang, Pengfei Guan, Jun Jack Hu, Keqi Tang. (2020) A TIMS-TOF mass spectrometry study of disaccharides from in situ ESI derivatization with 3-pyridinylboronate. ANALYST, 146 (1): (75-84). [PMID:33283797] [10.1039/D0AN01677B] |
| 8. Yong Li, Tingting Yang, Qing Yao, Songsong Li, En Fang, Yankun Li, Chao Liu, Weimin Li. (2019) Metformin prevents colonic barrier dysfunction by inhibiting mast cell activation in maternal separation-induced IBS-like rats. NEUROGASTROENTEROLOGY AND MOTILITY, 31 (5): (e13556). [PMID:30740845] [10.1111/nmo.13556] |
| 9. Tengfei Bian, Xiujuan Zhang, Gaohong He, Zhijun Duan, Chunxu Dong, Xiangcun Li, Nana Guo. (2017) Citric acid-loaded W1/O/W2 multiple emulsions efficiently remove colonic ammonia both in vitro and in vivo. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, [PMID:] [10.1080/01932691.2015.1038750] |
| 10. Hu Xu, Mukan Ji, Dawei Xu, Yongqin Liu. (2024) Computer-aided mining of a psychrophilic cellobiose 2-epimerase from the Qinghai-Tibet Plateau gene catalogue. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39089546] [10.1016/j.ijbiomac.2024.134202] |
| 11. Kaigang An, Xin Li, Jia Chen, Shuang Zhang, Jing Xiao, Qing Wang, Hongdeng Qiu. (2024) Deep eutectic solvent-assisted synthesis of La–Ce hybrid nanorods for the colorimetric determination of tetracycline in foods. Analytical Methods, 16 (22): (3551-3561). [PMID:38780040] [10.1039/D4AY00412D] |
| 12. Chenlu Zhu, Renjiao Han, Bixuan Gu, Caiyun Wang, Han Liu, Xiaomei Lyu, Jian He, Ruijin Yang. (2024) Multiple Regulatory Mechanisms Synergistically Control the Soluble Expression of CsCE for Enhanced Enzymatic Productivity of Lactulose in E. coli. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:39361812] [10.1021/acs.jafc.4c04060] |
| 13. Chenlu Zhu, Jian He, Jiali Gu, Xiaomei Lyu, Renjiao Han, Han Liu, Caiyun Wang, Ruijin Yang. (2025) Synthesis of lactulose via semi-rational design Aided evolution of glucose isomerase. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.106094] |
| 14. Zhong Chenggang, Ding Weijian, Lin Haoran, Huang Jin. (2025) Improved biosynthesis of lactulose by a novel thermostable cellobiose-2-epimerase generated through semi-rational mutagenesis. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 41 (11): (451). [PMID:41217547] [10.1007/s11274-025-04683-2] |
| 15. Zhiyong Liao, Ruizhe Zhang, Yongbo Fan, Lixing Song, Fang Yan, Ning Yang, Peizhi Dong, Zhuo Zhang, Zexue Lin, Weijia Wang, Huiqing Fan. (2025) Lactulose modulation of the inner Helmholtz plane for stable and dendrite-free zinc anodes in aqueous Zn-ion batteries. Journal of Materials Chemistry A, 13 (24): (18814-18823). [PMID:] [10.1039/D5TA00994D] |
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