LDN 193188 - ≥99%(HPLC) , CAS No.1267610-30-9

CAS: 1267610-30-9 Cat. No.: L287465 Formula: C₂₀H₁₇Cl₂N₅O₄S Peso molecolare: 494.35

GRADE & PURITY ≥99%(HPLC)

Synonyms

2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Product Describtion:

Inhibitor of phosphatidylcholine transfer protein (PC-TP)

Specifications

Sinonimi

2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide

Specifiche e purezza

≥99%(HPLC)

Meccanismi biochimici e fisiologici

Inhibitor of phosphatidylcholine transfer protein (PC-TP). Regulates hepatic glucose metabolism. Also promotes insulin-independent phosphorylation of key insulin signaling molecules.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥99%(HPLC)

Nomi e identificatori

• Pubchem Sid: 504771867
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504771867
• Sorrisi canonici: CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C
• IUPAC Name: 2,4-dichloro-N-[[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]carbamoyl]benzamide
• InChIKey: COTBDKMEUUNJTI-UHFFFAOYSA-N
• INCHI: 1S/C20H17Cl2N5O4S/c1-11-9-12(2)24-19(23-11)27-32(30,31)15-6-4-14(5-7-15)25-20(29)26-18(28)16-8-3-13(21)10-17(16)22/h3-10H,1-2H3,(H,23,24,27)(H2,25,26,28,29)
• Isomeri SMILES: CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)NC(=O)C3=C(C=C(C=C3)Cl)Cl)C
• Peso molecolare: 494.35
• Reaxy-Rn: 21195324
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21195324&ln=

Obiettivi associati (umani)

STARD7 Tbio StAR-related lipid transfer protein 7, mitochondrial (7 Activities)

Discover Target: STARD7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PCTP Tbio Phosphatidylcholine transfer protein (43 Activities)

Discover Target: PCTP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Solvent:DMSO, Max Conc. mg/mL: 49.44, Max Conc. mM: 100
• Peso molecolare: 494.300 g/mol
• XLogP3: 4.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 493.038 Da
• Monoisotopic Mass: 493.038 Da
• Topological Polar Surface Area: 139.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 762.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product, and how is it determined?

This product is supplied at ≥99% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1267610-30-9, the molecular formula is C20H17Cl2N5O4S, and the molecular weight is 494.35 g/mol. InChIKey COTBDKMEUUNJTI-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.