Lentinan - 10mM in DMSO , CAS No.37339-90-5

CAS: 37339-90-5 Cat. No.: L423679 PubChem CID: 37723

GRADE & PURITY 10mM in DMSO

Synonyms

LENTINAN|37339-90-5|Bromoduline|Biomoduline|LC-33|UNII-6751655D1D|DRG-0171|Lentinan(Biomoduline)|SCHEMBL1517264|DTXSID30190781|AKOS040758705|6751655D1D|E80771|A823605|(2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[[(2S,3R,4S,5R,6R)-4-[[(2S,3R,4S,5R,6R)-4-[[(2S,

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Lentinan Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

Specifications

Sinonimi

LENTINAN | 37339-90-5 | Bromoduline | Biomoduline | LC-33 | UNII-6751655D1D | DRG-0171 | Lentinan(Biomoduline) | SCHEMBL1517264 | DTXSID30190781 | AKOS040758705 | 6751655D1D | E80771 | A823605 | (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[[(2S,3R,4S,5R,6R)-4-[[(2S,3R,4S,5R,6R)-4-[[(2S,

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Lentinan (A823605, Bromoduline), isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

• Pubchem Sid: 528776540
• Sorrisi canonici: C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)CO)O)OC5C(C(C(C(O5)COC6C(C(C(C(O6)CO)O)O)O)O)OC7C(C(C(C(O7)CO)O)O)O)O)O)O)O)O)O)O)O
• IUPAC Name: (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChIKey: MAXBMUKIXLNXGX-DMWITZOWSA-N
• INCHI: 1S/C42H72O36/c43-1-8-15(48)22(55)25(58)37(69-8)66-6-13-20(53)32(28(61)36(65)68-13)75-40-29(62)33(18(51)11(4-46)72-40)77-41-30(63)34(19(52)12(5-47)73-41)78-42-31(64)35(76-39-27(60)24(57)17(50)10(3-45)71-39)21(54)14(74-42)7-67-38-26(59)23(56)16(49)9(2-44)70-38/h8-65H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25-,26-,27-,28-,29-,30-,31-,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42+/m1/s1
• Isomeri SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O)O)O)O)O)O)O)O
• PubChem CID: 37723

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Classe Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Classe: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Oligosaccharides
• Alternative Parents: O-glycosyl compounds Oxanes Secondary alcohols Hemiacetals Polyols Oxacyclic compounds Acetals Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Oligosaccharide - O-glycosyl compound - Glycosyl compound - Oxane - Secondary alcohol - Hemiacetal - Oxacycle - Organoheterocyclic compound - Polyol - Acetal - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as oligosaccharides. These are carbohydrates made up of 3 to 10 monosaccharide units linked to each other through glycosidic bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Punto di fusione (°C): 165° C
• Peso molecolare: 1153.000 g/mol
• XLogP3: -13.300
• Hydrogen Bond Donor Count: 23
• Hydrogen Bond Acceptor Count: 36
• Rotatable Bond Count: 19
• Exact Mass: 1152.38 Da
• Monoisotopic Mass: 1152.38 Da
• Topological Polar Surface Area: 585.000 Ų
• Heavy Atom Count: 78
• Formal Charge: 0
• Complexity: 1820.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 35
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Riferimenti

1. Yani Zou, Helin Xu, Xiu Wu, Xuesong Liu, Jianfu Zhao.  (2024)  Enhancing Radiotherapy Sensitivity in Prostate Cancer with Lentinan-Functionalized Selenium Nanoparticles: Mechanistic Insights and Therapeutic Potential.  Pharmaceutics,  16  (9): (1230).  [PMID:39339266] [10.3390/pharmaceutics16091230]

2. Yiting Yang, Ping Ren, Ying Sun, Junyi Li, Xinjun Zhou, Haipeng Zhang, Chengguang He, Huining Dai, Lili Guan.  (2024)  Structure elucidation and molecular mechanism of an immunomodulatory polysaccharide from Nostoc commune.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39537070] [10.1016/j.ijbiomac.2024.137435]

3. Xiao-liang Zhao, Zheng-lei Guo, Kai-li Qi, Qing-song Zhou, Yan-mei Liu, Li-xia Xiong, Jing Zhang, Ji Zhang, Wei-jie Zhang.  (2024)  The Polysaccharides from Pinellia ternata and Their Derivatives: Preparation, Structure Characteristics, and Activities in Vitro.  CHEMISTRY & BIODIVERSITY,  21  (8): (e202400596).  [PMID:38804585] [10.1002/cbdv.202400596]

4. Jingbo Zhang, Yajing Bai, Xiaoxue Zhang, Yiyao Wang, Zongshu Li, Chengguang He, Lili Guan.  (2025)  Impacts of Six Methods of Extraction on Physicochemical Properties, Structural Characteristics and Bioactivities of Polysaccharides from Pholiota nameko Residue.  Foods,  14  (17): (3071).  [PMID:40941187] [10.3390/foods14173071]

5. Wenqi Liu, Ying Sun, Yansheng Zhao, Fengxiang Liang, Yunxiang Que, Jing Yang, Lili Guan.  (2025)  Comparative study on extraction procedures for polysaccharides from safflower post-extraction residue: Structural characterization and bioactivity evaluation.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2025.121966]

6. Xiaoliang Zhao, Qingsong Zhou, He Mou, Li Ma, Yanmei Liu, Kaili Qi, Cunjin Wang, Jing Zhang, Ji Zhang, Weijie Zhang.  (2025)  Sulfated modification of polysaccharides from Sophora flavescens: Impact on antioxidant, antitumor, and immunomodulatory activities.  FITOTERAPIA,      [PMID:40258430] [10.1016/j.fitote.2025.106560]

7. Tiankai Bai, Zhilong Shi, Shuguang Bao, Xiaorong Hou, Yuping Zhao, Wai L.W. Leung, Yuhui Li, Sirigunqiqige Pan, Ying Xin, Ye Luo, Xiaohe Xiao, Laxinamujila Bai, Huifang Li.  (2025)  The structural discrepancy in the immunomodulatory potency of the polysaccharides RFHP-1 and RFHP-2 derived from Radix Fici Hirtae.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40403788] [10.1016/j.ijbiomac.2025.144432]

8. Xue Chang, Zhou Yicheng, Lin Huixin, Li Zijun, Xiao Yuxin, Yang Jinfeng, Lu Mengqi, Qin Yuwen, Song Dawei, Chen Wei, Xu Junpeng, Zuo Yanming, Wang Zhouguang, Jiang Chengxi.  (2026)  A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation.  JOURNAL OF NANOBIOTECHNOLOGY,  24  (1): (158).  [PMID:41673859] [10.1186/s12951-026-04114-w]

9. Xiaoliang Zhao, Lixia Xiong, Haidong Wen, Yuanyuan Ma, Yuxin Wang, Cunjin Wang, Pengcheng Shao, Jing Zhang, Yuhui Zhao, Ji Zhang, Weijie Zhang.  (2026)  Ultrasound-Assisted Extraction, Chemical Modification, Structural Characterization, and Activity Studies of Polysaccharides From Corn Silk.  CHEMISTRY & BIODIVERSITY,  23  (3): (e03369).  [PMID:41852144] [10.1002/cbdv.202503369]