LG 100754 - Moligand™, ≥98% , Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ, CAS No.180713-37-5, Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ
LG 100754 - Moligand™, ≥98% , Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ, CAS No.180713-37-5, Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ
GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
Application:
LG100754 (UVI 2112) is a modulator of RXR dimers. LG100754 acts as an antagonist of the homodimeric RXR:RXR, but as an agonist of the heterodimeric RXR:PPARα and RXR:PPARγ. LG100754 is an insulin sensitizer acting through RXR.
LG100754 is a unique RXR ligand that acts as an antagonist against RXR homodimers, but is a strong agonist for RXR:PPARα and RXR:PPARγ heterodimers. The compound does not have agonist activities for other RXR heterodimers containing LXR or GAR/FXR recepto
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Grado
Moligand™
Tipo di azione
AGONIST, ANTAGONIST
Meccanismo d'azione
Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ
This compound belongs to the class of organic compounds known as retinoids. These are oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Proprietà chimiche e fisiche
Solubilità
Solvent:DMSO, Max Conc. mg/mL: 39.66, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 19.83, Max Conc. mM: 50
Peso molecolare
396.600 g/mol
XLogP3
8.400
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
7
Exact Mass
396.266 Da
Monoisotopic Mass
396.266 Da
Topological Polar Surface Area
46.500 Ų
Heavy Atom Count
29
Formal Charge
0
Complexity
665.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
3
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
3
Covalently-Bonded Unit Count
1
Calcolatori di soluzioni
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Recensioni
Recensioni dei clienti
Domande frequenti
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 180713-37-5, the molecular formula is C26H36O3, and the molecular weight is 396.56 g/mol. InChIKey HNODNXQAYXJFMQ-LQUSFLDPSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Need help choosing the grade?
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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