Luminol sodium salt - Moligand™,≥98%(HPLC) , CAS No.20666-12-0

CAS: 20666-12-0 Cat. No.: L168455 Molecular Weight: 199.14 EC Number: 629-344-5

GRADE & PURITY Moligand™, ≥98%(HPLC)

Synonyms

KFG2PZR7UX | BCP13343 | o-Aminophthalylhydrazide sodium | N-[3-(3-aminopropoxy)benzyl] piperidine | (S)-(+)-7,8-Dihydrokavain | Luminol sodium salt | 3-Aminophthalhydrazide monosodium salt | LUMINOL MONOSODIUM | W15451 | BLACK SULFIDE OF MERCURY | Galavit

Storage

Protected from light,Room temperature

Shipped In

Normal

Overview

Used for chemiluminescence analysis, such as in the analysis of metal cations, blood, and glucocorticoids; it can also be used in vivo to image bone marrow peroxidase activity.

Luminol sodium salt is a chemiluminescent substance with pKa values ​​of 6.74 and 15.1. The optimal fluorescence wavelength for  Luminol sodium salt is 425 nm.  Luminol sodium salt is commonly used as a diagnostic tool in forensic bloodstain detection and has applications in criminal investigation, bioengineering, and chemical tracing.

Applications

Luminol sodium salt has been used for:

1. As a component of MEBSS buffer in bioluminescent assays to detect peroxidase activity in whole blood samples;

2. Immunoprecipitation analysis of protein interactions in whole cell lysates;

3. Quantification of reactive oxygen species (ROS) in CD45+ and CD45− cells in vitro.

Specifications

Synonyms

KFG2PZR7UX | BCP13343 | o-Aminophthalylhydrazide sodium | N-[3-(3-aminopropoxy)benzyl] piperidine | (S)-(+)-7, 8-Dihydrokavain | Luminol sodium salt | 3-Aminophthalhydrazide monosodium salt | LUMINOL MONOSODIUM | W15451 | BLACK SULFIDE OF MERCURY | Galavit

Specifications & Purity

Moligand™, ≥98%(HPLC)

Biochemical and Physiological Mechanisms

Luminol is a chemiluminescent compound that is sensitive to redox reactions. When the alkaline aqueous solution of luminol containing oxygen atoms comes into contact with oxidants such as potassium ferrocyanide, it emits blue light. This component has hig

Storage

Protected from light, Room temperature

Shipped In

Normal

Grade

Moligand™

Purity

≥98%(HPLC)

Names and Identifiers

• Pubchem Sid: 504767866
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504767866
• Canonical Smiles: C1=CC2=C(C(=C1)N)C(=O)N[N-]C2=O.[Na+]
• IUPAC Name: sodium;8-amino-2H-phthalazin-3-ide-1,4-dione
• InChIKey: RVJVDCVIJCBUTH-UHFFFAOYSA-M
• INCHI: 1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1
• Isomeric SMILES: C1=CC2=C(C(=C1)N)C(=O)N[N-]C2=O.[Na+]
• Molecular Weight: 199.14
• Reaxy-Rn: 11612736
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11612736&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Diazanaphthalenes
      • Subclass Benzodiazines
        • Level5 Phthalazines
          • Level6 Phthalazinones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Phthalazines
• Direct Parent: Phthalazinones
• Alternative Parents: Pyridazinones Benzenoids Vinylogous amides Heteroaromatic compounds Lactams Azacyclic compounds Primary amines Organooxygen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phthalazinone - Pyridazinone - Pyridazine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Lactam - Azacycle - Organic alkali metal salt - Organic oxide - Organic salt - Organic zwitterion - Organic oxygen compound - Amine - Primary amine - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organic sodium salt - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as phthalazinones. These are compounds containing a phthalazine bearing a ketone group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (50 mg/ml)
• Sensitivity: Hygroscopic；light sensitive
• Molecular Weight: 199.140 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 199.036 Da
• Monoisotopic Mass: 199.036 Da
• Topological Polar Surface Area: 73.200 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 259.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3