Macrosporin - ≥98% , CAS No.22225-67-8

CAS: 22225-67-8 Cat. No.: M329498 Formula: C₁₆H₁₂O₅ Peso molecolare: 284.26

GRADE & PURITY ≥98%

Synonyms

BDBM50480484 | SCHEMBL16227189 | 1,7-DIHYDROXY-3-METHOXY-6-METHYL-9,10-DIHYDROANTHRACENE-9,10-DIONE | 9,10-Anthracenedione, 1,7-dihydroxy-3-methoxy-6-methyl- | 1,7-dihydroxy-3-methoxy-6-methyl-9,10-anthraquinone | J-014592 | DTXSID50176769 | Macrosporin |

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Macrosporin is an anthraquinone antibiotic. Macrosporin is described to produce antibacterial growth inhibition against|Bacillus subtilis|and|Staphylococcus aureus|in agar diffusion assays.

Specifications

Sinonimi

BDBM50480484 | SCHEMBL16227189 | 1,7-DIHYDROXY-3-METHOXY-6-METHYL-9,10-DIHYDROANTHRACENE-9,10-DIONE | 9,10-Anthracenedione, 1,7-dihydroxy-3-methoxy-6-methyl- | 1,7-dihydroxy-3-methoxy-6-methyl-9,10-anthraquinone | J-014592 | DTXSID50176769 | Macrosporin |

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: CC1=CC2=C(C=C1O)C(=O)C3=C(C2=O)C=C(C=C3O)OC
• IUPAC Name: 1,7-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione
• InChIKey: FKTPLNFTYJEAAB-UHFFFAOYSA-N
• INCHI: 1S/C16H12O5/c1-7-3-9-10(6-12(7)17)16(20)14-11(15(9)19)4-8(21-2)5-13(14)18/h3-6,17-18H,1-2H3
• Isomeri SMILES: CC1=CC2=C(C=C1O)C(=O)C3=C(C2=O)C=C(C=C3O)OC
• Peso molecolare: 284.26
• Reaxy-Rn: 2221069
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2221069&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Anthracenes
      • Subclass Anthraquinones

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Anthracenes
• Subclass: Anthraquinones
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydroxyanthraquinones
• Alternative Parents: Aryl ketones Anisoles Alkyl aryl ethers 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Vinylogous acids Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Hydroxyanthraquinone - Aryl ketone - Anisole - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Vinylogous acid - Ketone - Ether - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as hydroxyanthraquinones. These are compounds containing a hydroxyanthraquinone moiety, which consists of an anthracene bearing a quinone, and hydroxyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

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INSR Tclin Insulin receptor (5558 Activities)

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ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)

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PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 Activities)

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IGF1R Tclin Insulin-like growth factor I receptor (8605 Activities)

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CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)

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SRC Tclin Tyrosine-protein kinase SRC (10310 Activities)

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AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 Activities)

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PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

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KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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PTK2 Tclin Focal adhesion kinase 1 (4730 Activities)

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MET Tclin Hepatocyte growth factor receptor (10718 Activities)

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CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

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FLT4 Tclin Vascular endothelial growth factor receptor 3 (3216 Activities)

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AKT1 Tchem Serine/threonine-protein kinase AKT (9192 Activities)

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FLT3 Tclin Tyrosine-protein kinase receptor FLT3 (13481 Activities)

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TEK Tclin Tyrosine-protein kinase TIE-2 (3348 Activities)

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AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)

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PLK4 Tchem Serine/threonine-protein kinase PLK4 (1882 Activities)

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A549 (127892 Activities)

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BRAF Tclin Serine/threonine-protein kinase B-raf (11587 Activities)

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EPHB4 Tchem Ephrin type-B receptor 4 (3198 Activities)

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MAP3K8 Tchem Mitogen-activated protein kinase kinase kinase 8 (459 Activities)

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NUAK1 Tchem NUAK family SNF1-like kinase 1 (1769 Activities)

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CDK4 Tclin Cyclin-dependent kinase 4/cyclin D1 (2340 Activities)

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Obiettivi associati (non umani)

Vibrio parahaemolyticus (473 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Staphylococcus (1598 Activities)

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Aspergillus flavus (8875 Activities)

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Bacillus subtilis (32866 Activities)

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Bacillus cereus (7522 Activities)

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L5178Y (1809 Activities)

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Fusarium verticillioides (912 Activities)

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Micrococcus (119 Activities)

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Kocuria rhizophila (337 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Soluble in DMSO or 100% ethanol.
• Peso molecolare: 284.260 g/mol
• XLogP3: 3.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 284.068 Da
• Monoisotopic Mass: 284.068 Da
• Topological Polar Surface Area: 83.800 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 448.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1