Maslinic acid - Moligand™, ≥98% , CAS No.4373-41-5

CAS: 4373-41-5 Cat. No.: M138841 Formula: C₃₀H₄₈O₄ Peso molecolare: 472.7

GRADE & PURITY Moligand™, ≥98%

Synonyms

CHEBI:66682 | LMPR0106180014 | Maslinic acid, >=98% (HPLC) | Q-101529 | AC-33937 | 2a-Hydroxyoleanoic Acid | C16939 | Crataegolic acid | Diethylamid kyseliny mravenci | (2.alpha.,3.beta.)-2,3-dihydroxy-Olean-12-en-28-oate | HMS3886H14 | HSDB 8099 | Lysine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinonimi

CHEBI:66682 | LMPR0106180014 | Maslinic acid, >=98% (HPLC) | Q-101529 | AC-33937 | 2a-Hydroxyoleanoic Acid | C16939 | Crataegolic acid | Diethylamid kyseliny mravenci | (2.alpha.,3.beta.)-2,3-dihydroxy-Olean-12-en-28-oate | HMS3886H14 | HSDB 8099 | Lysine

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

Maslinic acid is a powerful antioxidant and anti-inflammatory. Besides being a good anticancer agent, it also has antidiabetic and antiparasitic properties. Maslinic acid has neuroprotective and cardioprotective effects. It is reported to be a multi-targe

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 504754720
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504754720
• Sorrisi canonici: CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1)C)C(=O)O)C
• IUPAC Name: (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
• InChIKey: MDZKJHQSJHYOHJ-LLICELPBSA-N
• INCHI: 1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1
• Isomeri SMILES: C[C@@]12CC[C@@H]3[C@@]([C@H]1CC=C4[C@]2(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)(C[C@H]([C@@H](C3(C)C)O)O)C
• Peso molecolare: 472.7
• Reaxy-Rn: 2711870
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2711870&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Prenol lipids
      • Subclass Triterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Prenol lipids
• Subclass: Triterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Triterpenoids
• Alternative Parents: Secondary alcohols Cyclic alcohols and derivatives 1,2-diols Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Triterpenoid - Cyclic alcohol - Secondary alcohol - 1,2-diol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
• External Descriptors: Ursanes

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

AKR1B10 Tchem Aldo-keto reductase family 1 member B10 (1 Activities)

Discover Target: AKR1B10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

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ACHE Tclin Acetylcholinesterase (18204 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

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AKR1B1 Tclin Aldose reductase (1404 Activities)

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PTPN2 Tchem T-cell protein-tyrosine phosphatase (1317 Activities)

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ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

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PYGM Tchem Muscle glycogen phosphorylase (197 Activities)

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PTPN6 Tchem Protein-tyrosine phosphatase 1C (687 Activities)

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PTPN11 Tchem Protein-tyrosine phosphatase 2C (2297 Activities)

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PTPRF Tchem Receptor-type tyrosine-protein phosphatase F (LAR) (718 Activities)

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DLD-1 (17511 Activities)

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HT-29 (80576 Activities)

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MCF7 (126967 Activities)

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MT2 (2907 Activities)

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NCI-N87 (850 Activities)

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Raji (5516 Activities)

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SW-1736 (356 Activities)

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A253 cell line (154 Activities)

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A549 (127892 Activities)

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FaDu (1726 Activities)

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HepG2 (196354 Activities)

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A2780 (11979 Activities)

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KB (17409 Activities)

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Lu1 (576 Activities)

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AKR1B10 Tchem Aldo-keto reductase family 1 member B10 (300 Activities)

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8505C (583 Activities)

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PRKAA2 Tchem AMP-activated protein kinase, AMPK (12273 Activities)

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EGLN2 Tclin Hypoxia-inducible factor prolyl hydroxylase (45 Activities)

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Obiettivi associati (non umani)

Pygl Liver glycogen phosphorylase (81 Activities)

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Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)

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Artemia salina (1320 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Bacillus thuringiensis (718 Activities)

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Enterococcus faecalis (29875 Activities)

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Plasmodium falciparum (966862 Activities)

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Toxoplasma gondii (4585 Activities)

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Spodoptera littoralis (798 Activities)

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Mus musculus (284745 Activities)

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Human immunodeficiency virus 1 (70413 Activities)

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Hepatitis C virus (23859 Activities)

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Influenza A virus (11224 Activities)

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MDCK (10148 Activities)

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RAW264.7 (28094 Activities)

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Vero (26788 Activities)

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BV-2 (3710 Activities)

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NIH3T3 (5395 Activities)

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B16-F10 (4610 Activities)

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PYGM Glycogen phosphorylase, muscle form (1331 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Protease (18 Activities)

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BCHE Cholinesterase (8742 Activities)

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Ileum (29 Activities)

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Influenza A virus H3N2 (588 Activities)

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SARS-CoV-2 (38078 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: acetone: 1 mg/mL, clear, colorless
• Sensibilità: Heat sensitive
• Peso molecolare: 472.700 g/mol
• XLogP3: 6.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 472.355 Da
• Monoisotopic Mass: 472.355 Da
• Topological Polar Surface Area: 77.800 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 919.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 9
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Riferimenti

1. Lu Huang, Yingjie Guo, Tianqi Jin, Ke Yan, Xianglin Liu, Shuyang He, Lin Li, Ye Gong, Junyi Ma, Hang Yu, Zhoumin Lu, Yupeng Liu, Wuzi Dong, Fangxia Yang.  (2023)  Extraction of triterpene acids from loquat leaves via a novel hydrophobic deep eutectic solvent screened by COSMO-SAC model.  Journal of Cleaner Production,      [PMID:] [10.1016/j.jclepro.2023.139274]

2. Heran Cao, Zhenpeng Li, Tianqi Jin, Shuyang He, Shujuan Liu, Long Li, Yang Wang, Ye Gong, Gang Wang, Fangxia Yang, Wuzi Dong.  (2023)  Maslinic acid supplementation prevents di(2-ethylhexyl) phthalate-induced apoptosis via PRDX6 in peritubular myoid cells of Chinese forest musk deer.  Journal of Environmental Sciences,      [PMID:38644023] [10.1016/j.jes.2023.07.034]

Domande frequenti

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 4373-41-5, the molecular formula is C30H48O4, and the molecular weight is 472.7 g/mol. InChIKey MDZKJHQSJHYOHJ-LLICELPBSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.