≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
2,2-Dimethyl-1,3-dioxane-4,6-dione (Meldrum′s acid) is widely used in organic synthesis, especially for multiple C-C bond formations due to its adequate acidity (pKa 4.83) and steric rigidity. Knoevenagel condensation reaction between aldehydes and Meldrum′s acid are accelerated in ionic liquids.
Usually used in the synthesis of macrocyclic β-keto lactone,4-pyridyl-substituted heterocycles,2-substituted indoles, isofraxidin.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Classe | Organooxygen compounds |
| Subclass | Ethers |
| Intermediate Tree Nodes | Acetals |
| Direct Parent | Ketals |
| Alternative Parents | Dicarboxylic acids and derivatives 1,3-dioxanes 1,3-dicarbonyl compounds Lactones Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Ketal - 1,3-dicarbonyl compound - Dicarboxylic acid or derivatives - Meta-dioxane - Lactone - Carboxylic acid ester - Oxacycle - Organoheterocyclic compound - Carboxylic acid derivative - Organic oxide - Hydrocarbon derivative - Carbonyl group - Aliphatic heteromonocyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as ketals. These are acetals derived from ketones by replacement of the oxo group by two hydrocarbyloxy groups R2C(OR)2 ( R not Hydrogen ). This term, once abandoned, has been reinstated as a subclass of acetals. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
 L2202148 | Certificate of Analysis | Sep 01, 2026 | M110151 |
| G2510012 | Certificate of Analysis | Aug 02, 2025 | M110151 |
| H2408604 | Certificate of Analysis | Jul 29, 2024 | M110151 |
| F2622039 | Certificate of Analysis | Jul 29, 2024 | M110151 |
| C2429651 | Certificate of Analysis | Mar 08, 2024 | M110151 |
| C2429652 | Certificate of Analysis | Mar 08, 2024 | M110151 |
| C2429650 | Certificate of Analysis | Mar 08, 2024 | M110151 |
| F2330811 | Certificate of Analysis | Jun 14, 2023 | M110151 |
| F2330825 | Certificate of Analysis | Jun 14, 2023 | M110151 |
| F2330827 | Certificate of Analysis | Jun 14, 2023 | M110151 |
| F2330828 | Certificate of Analysis | Jun 14, 2023 | M110151 |
| J2309051 | Certificate of Analysis | Jun 14, 2023 | M110151 |
| K2202148 | Certificate of Analysis | Oct 11, 2022 | M110151 |
| K2202175 | Certificate of Analysis | Oct 11, 2022 | M110151 |
| E2615174 | Certificate of Analysis | Oct 11, 2022 | M110151 |
| L2201202 | Certificate of Analysis | Oct 11, 2022 | M110151 |
| L2201427 | Certificate of Analysis | Oct 11, 2022 | M110151 |
| L2202175 | Certificate of Analysis | Oct 11, 2022 | M110151 |
| E2330116 | Certificate of Analysis | Oct 27, 2021 | M110151 |
| Solubilità | Soluble in water. Slightly soluble in ethanol and chloroform. |
|---|---|
| Sensibilità | heat sensitive |
| Punto di fusione (°C) | 95°C |
| Peso molecolare | 144.120 g/mol |
| XLogP3 | 0.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 0 |
| Exact Mass | 144.042 Da |
| Monoisotopic Mass | 144.042 Da |
| Topological Polar Surface Area | 52.600 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 164.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
