Meprednisone - 10mM in DMSO , Glucocorticoid receptor agonist, CAS No.1247-42-3, Glucocorticoid receptor agonist

CAS: 1247-42-3 Cat. No.: M408621 Formula: C₂₂H₂₈O₅ Peso molecolare: 372.455 Numero EC: 214-996-1

GRADE & PURITY 10mM in DMSO

Synonyms

NSC 527579, SCH 4358 | (16β)​-17,​21-​dihydroxy-​16-​methyl-​pregna-​1,​4-​diene-​3,​11,​20-​trione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Meprednisone Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.
In vitro

In vivo

Cell Data

cell lines：PM1 cells

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Sinonimi

NSC 527579, SCH 4358 | (16β)​-17,​21-​dihydroxy-​16-​methyl-​pregna-​1,​4-​diene-​3,​11,​20-​trione

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

AGONIST

Meccanismo d'azione

Glucocorticoid receptor agonist

Proprietà del prodotto

• ALogP: 1.9

Nomi e identificatori

• Isomeri SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@H]3C(=O)C[C@@]2([C@]1(C(=O)CO)O)C)C
• Peso molecolare: 372.455
• Reaxy-Rn: 3481452
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3481452&ln=

Proprietà chimiche e fisiche

• Punto di fusione (°C): 204-206°C

Riferimenti

1. Jianbo Li, Ertai Ye, Jingwen Huang, Meng Xu, Jieke Zhang, Junrong Zhang, Huijie Cai, Jinjie Zhang.  (2024)  Cysteine-modified PEGylated nanoparticles for targeted delivery of methylprednisolone to pancreatitis.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:38199584] [10.1016/j.ejpb.2024.114179]

Domande frequenti

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1247-42-3, the molecular formula is C22H28O5, and the molecular weight is 372.455 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.