Meprednisone - 10mM in DMSO , Glucocorticoid receptor agonist, CAS No.1247-42-3, Glucocorticoid receptor agonist

CAS: 1247-42-3 Cat. No.: M408621 Molecular Weight: 372.455 EC Number: 214-996-1
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Synonyms
NSC 527579, SCH 4358 | (16β)​-17,​21-​dihydroxy-​16-​methyl-​pregna-​1,​4-​diene-​3,​11,​20-​trione
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
M408621-1ml
1

$130.90

$189.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Meprednisone Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.
In vitro


In vivo


Cell Data

cell lines:PM1 cells

Concentrations:

Incubation Time:

Powder Purity:≥98%

Specifications

Synonyms
NSC 527579, SCH 4358 | (16β)​-17, ​21-​dihydroxy-​16-​methyl-​pregna-​1, ​4-​diene-​3, ​11, ​20-​trione
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
AGONIST
Mechanism of action
Glucocorticoid receptor agonist
Product Properties
ALogP1.9
Names and Identifiers
Isomeric SMILES C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@H]3C(=O)C[C@@]2([C@]1(C(=O)CO)O)C)C
Molecular Weight 372.455
Reaxy-Rn 3481452
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3481452&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)204-206°C
Citations of This Product
References
1. Jianbo Li, Ertai Ye, Jingwen Huang, Meng Xu, Jieke Zhang, Junrong Zhang, Huijie Cai, Jinjie Zhang.  (2024)  Cysteine-modified PEGylated nanoparticles for targeted delivery of methylprednisolone to pancreatitis.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:38199584] [10.1016/j.ejpb.2024.114179]
Solution Calculators
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