Methoxy poly(ethylene glycol) KAT - PEG average Mₙ 20,000

Cat. No.: M475643

GRADE & PURITY PEG average Mₙ 20,000

Synonyms

mPEG KAT, KAT PEG 20k

Storage

Store at 2-8°C

Shipped In

Wet ice

Panoramica

Description

Methoxy poly(ethylene glycol) KAT 20K (mPEG KAT 20K) is a monofunctional, methyl ether PEG featuring a terminal potassium acyltrifluoroborate for facile, rapid functionalization. Potassium acyltrifluoroborates (KATs) are stable functional groups that undergo rapid amide-forming ligations with hydroxylamines in aqueous media, in the presence of unprotected functional groups. In addition to its compatibility, these reactions proceed relatively quickly, lending to their use with sensitive biological reagents. This conjugation reaction offers a new approach to the synthesis of complex molecules without the complication of side reactions, such protein-polymer conjugates. KATs also undergo amide or imide-forming ligations in acidic conditions when reacted with primary amines or amides, respectively, as an alternative to classical acylation chemistry.}

Specifications

Sinonimi

mPEG KAT, KAT PEG 20k

Specifiche e purezza

PEG average Mₙ 20,000

Condizioni di conservazione di stoccaggio

Store at 2-8°C

Spedito in

Wet ice

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