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· · COA & SDS Disponibile per ogni prodotto · Spedizione lo stesso giorno su articoli in magazzino Home Per obiettivo / percorso / malattia Tramite vie di segnalazione PI3K/Akt/mTOR Atto Miransertib - Moligand™, 10mM in DMSO , Allosteric modulator of AKT serine/threonine kinase 1;Inhibitor of AKT serine/threonine kinase 1;Allosteric modulator of AKT serine/threonine kinase 2;Inhibitor of AKT serine/threonine kinase 2;Allosteric modulator , Allosteric modulator of AKT serine/threonine kinase 1;Inhibitor of AKT serine/threonine kinase 1;Allosteric modulator of AKT serine/threonine kinase 2;Inhibitor of AKT serine/threonine kinase 2;Allosteric modulator of AKT serine/threonine kinase 3;Inhibit Miransertib - Moligand™, 10mM in DMSO , Allosteric modulator of AKT serine/threonine kinase 1;Inhibitor of AKT serine/threonine kinase 1;Allosteric modulator of AKT serine/threonine kinase 2;Inhibitor of AKT serine/threonine kinase 2;Allosteric modulator , Allosteric modulator of AKT serine/threonine kinase 1;Inhibitor of AKT serine/threonine kinase 1;Allosteric modulator of AKT serine/threonine kinase 2;Inhibitor of AKT serine/threonine kinase 2;Allosteric modulator of AKT serine/threonine kinase 3;Inhibit
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
1313881-70-7 | BDBM50593633 | D11409 | 3-(3-(4-(1-AMINOCYCLOBUTYL)PHENYL)-5-PHENYL-3HIMIDAZO(4,5-B)PYRIDIN-2-YL)PYRIDIN-2-AMINE | Miransertib [USAN] | T1DQI1B52Y | AI-942/25034199 | HY-19719 | (+/-) camphorsulfonic acid | ARQ 092 | F85345 | Miransertib [U
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions.
Specifications Sinonimi
1313881-70-7 | BDBM50593633 | D11409 | 3-(3-(4-(1-AMINOCYCLOBUTYL)PHENYL)-5-PHENYL-3HIMIDAZO(4,5-B)PYRIDIN-2-YL)PYRIDIN-2-AMINE | Miransertib [USAN] | T1DQI1B52Y | AI-942/25034199 | HY-19719 | (+/-) camphorsulfonic acid | ARQ 092 | F85345 | Miransertib [U
Specifiche e purezza
Moligand™, 10mM in DMSO
Meccanismi biochimici e fisiologici
Allosteric, selective, non-ATP competitive\xa0pan-Akt inhibitor (IC 50 = 5.0, 4.5, and 16 nM for Akt1, Akt2, and Akt3, respectively). Selective for Akt isoforms over a panel of 303 other kinases.
Condizioni di conservazione di stoccaggio
Protected from light,Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
ALLOSTERIC MODULATOR, INHIBITOR
Meccanismo d'azione
Allosteric modulator of AKT serine/threonine kinase 1;Inhibitor of AKT serine/threonine kinase 1;Allosteric modulator of AKT serine/threonine kinase 2;Inhibitor of AKT serine/threonine kinase 2;Allosteric modulator of AKT serine/threonine kinase 3;Inhibit
Proprietà del prodotto Nomi e identificatori Pubchem Sid 528765632 Sorrisi canonici C1CC(C1)(C2=CC=C(C=C2)N3C4=C(C=CC(=N4)C5=CC=CC=C5)N=C3C6=C(N=CC=C6)N)N IUPAC Name 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine InChIKey HNFMVVHMKGFCMB-UHFFFAOYSA-N INCHI 1S/C27H24N6/c28-24-21(8-4-17-30-24)25-32-23-14-13-22(18-6-2-1-3-7-18)31-26(23)33(25)20-11-9-19(10-12-20)27(29)15-5-16-27/h1-4,6-14,17H,5,15-16,29H2,(H2,28,30) Isomeri SMILES C1CC(C1)(C2=CC=C(C=C2)N3C4=C(C=CC(=N4)C5=CC=CC=C5)N=C3C6=C(N=CC=C6)N)N CAS alternativo 1313881-70-7 Termini MeSH 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo(4,5-b)pyridin-2-yl)pyridin-2-amine;ARQ 092;Miransertib Peso molecolare 432.53 Reaxy-Rn 21571033 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21571033&ln=
Documentazione 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Pyridines and derivatives Subclass Phenylpyridines Intermediate Tree Nodes Not available Direct Parent Phenylpyridines Alternative Parents Phenylimidazoles Imidazopyridines Aralkylamines Aminopyridines and derivatives N-substituted imidazoles Imidolactams Benzene and substituted derivatives Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 2-phenylpyridine - 1-phenylimidazole - Imidazopyridine - Aminopyridine - Aralkylamine - Imidolactam - Benzenoid - N-substituted imidazole - Monocyclic benzene moiety - Imidazole - Azole - Heteroaromatic compound - Azacycle - Amine - Primary amine - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Primary aliphatic amine - Organic nitrogen compound - Aromatic heteropolycyclic compound Descrizione This compound belongs to the class of organic compounds known as phenylpyridines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyridine ring through a CC or CN bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Peso molecolare 432.500 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 4 Exact Mass 432.206 Da Monoisotopic Mass 432.206 Da Topological Polar Surface Area 95.600 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 653.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Citations of This Product Riferimenti 1. Ming Luo, Yawei Du, Xuanchen Liu, Shuwen Zhang, Wenwen Zhu, Kaipeng Liu, Xiubao Ren, Ningning Zhang. (2025) Fecal Microbiota Transplantation Alleviates Cirrhotic Portal Hypertension in Rats via Butyrate-Mediated HDAC3 Inhibition and PI3K/Akt/eNOS Signaling Regulation. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:40441587 ] [10.1016/j.ejphar.2025.177781 ]
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Reconstitution Calculator Recensioni Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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